Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.70 |
| ▸ | GAA | P10253 | 2/20 | 0.70 |
| ▸ | POLB | P06746 | 4/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.68 |
| ▸ | TP53 | P04637 | 1/20 | 0.68 |
| ▸ | GLA | P06280 | 1/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.68 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.68 |
| ▸ | HPGD | P15428 | 1/20 | 0.68 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.68 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.68 |
| ▸ | APEX1 | P27695 | 1/20 | 0.68 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.56 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.54 |
| ▸ | DNMT1 | P26358 | 7/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22502343 | 1.00 | ALDH1A1 (0.70) | ALDH1A1GAAPOLBKDM4ETP53 | |
| SCHEMBL7429057 | 1.00 | ALDH1A1 (0.70) | ALDH1A1GAAPOLBKDM4ETP53 | |
| SCHEMBL6896852 | 0.86 | ALDH1A1 (0.79) | ALDH1A1GAAPOLBKDM4ETP53 | |
| SCHEMBL6896845 | 0.86 | ALDH1A1 (0.79) | ALDH1A1GAAPOLBKDM4ETP53 | |
| SCHEMBL512529 | 0.84 | ALDH1A1 (0.71) | ALDH1A1GAAPOLBKDM4ETP53 | |
| SCHEMBL22513798 | 0.84 | ALDH1A1 (0.69) | ALDH1A1GAAPOLBKDM4ETP53 | |
| SCHEMBL20835844 | 0.84 | ALDH1A1 (0.68) | ALDH1A1GAAPOLBKDM4ETP53 | |
| SCHEMBL512864 | 0.84 | ALDH1A1 (0.68) | ALDH1A1GAAPOLBKDM4ETP53 | |
| SCHEMBL4903634 | 0.84 | ALDH1A1 (0.68) | ALDH1A1GAAPOLBKDM4ETP53 | |
| SCHEMBL7288420 | 0.84 | ALDH1A1 (0.71) | ALDH1A1GAAPOLBKDM4ETP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8759582-B2 | Process for the preparation of lacosamide | NATCO PHARMA LIMITED (IN) | 2014-06-24 | — | — | US | disclosed |
| US-8759582-B2 | Process for the preparation of lacosamide | NATCO PHARMA LIMITED (IN) | 2014-06-24 | — | — | US | disclosed |
| US-20130035508-A1 | PROCESS FOR THE PREPARATION OF LACOSAMIDE | NATCO PHARMA LIMITED (IN) | 2013-02-07 | — | — | US | disclosed |
| US-20130035508-A1 | PROCESS FOR THE PREPARATION OF LACOSAMIDE | NATCO PHARMA LIMITED (IN) | 2013-02-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130035508-A1 | PROCESS FOR THE PREPARATION OF LACOSAMIDE | CA3, CACNA1A, CA2 | ALDH1A1 1559/4885GAA 259/4885POLB 2915/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.