Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 14/20 | 0.39 |
| ▸ | PPARG | P37231 | 8/20 | 0.39 |
| ▸ | PPARD | Q03181 | 8/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7428732 | 0.77 | SMN1; SMN2 (0.44) | FFAR1PPARGPPARDPPARAHDAC1 | |
| SCHEMBL3556105 | 0.73 | ALDH1A1 (0.53) | PPARGPPARAALDH1A1SMN1; SMN2 | |
| SCHEMBL12894958 | 0.71 | HDAC3 (0.51) | HDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL2892096 | 0.71 | HDAC3 (0.45) | HDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL7299608 | 0.71 | HDAC3 (0.45) | HDAC3HDAC1HDAC2NCOR2ALDH1A1 | |
| SCHEMBL27532350 | 0.71 | HDAC3 (0.45) | HDAC3HDAC1HDAC2NCOR2ALDH1A1 | |
| SCHEMBL10443342 | 0.70 | FFAR1 (0.44) | FFAR1PPARGPPARDPPARA | |
| SCHEMBL18586000 | 0.70 | HDAC1 (0.45) | HDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL7430593 | 0.69 | HDAC3 (0.36) | PPARGPPARAHDAC3HDAC1HDAC2 | |
| SCHEMBL28580843 | 0.69 | MIF (0.49) | FFAR1PPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0375451-A2 | Compounds having a renin-inhibiting activity | BEECHAM GROUP PLC (GB) | 1990-06-27 | — | — | EP | disclosed |