Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 15/20 | 0.56 |
| ▸ | ITGA4 | P13612 | 15/20 | 0.56 |
| ▸ | ITGB7 | P26010 | 7/20 | 0.56 |
| ▸ | ITGA2 | P17301 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | NOS2 | P35228 | 2/20 | 0.45 |
| ▸ | NOS3 | P29474 | 1/20 | 0.45 |
| ▸ | NOS1 | P29475 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6582622 | 1.00 | ITGB1 (0.56) | ITGB1ITGA4ITGB7ITGA2L3MBTL1 | |
| SCHEMBL12889768 | 0.94 | ITGB1 (0.49) | ITGB1ITGA4ITGB7ITGA2NOS2 | |
| SCHEMBL3316636 | 0.94 | ITGB1 (0.49) | ITGB1ITGA4ITGB7ITGA2NOS2 | |
| SCHEMBL6638679 | 0.92 | L3MBTL1 (0.55) | ITGB1ITGA4ITGB7ITGA2L3MBTL1 | |
| SCHEMBL6585927 | 0.90 | ITGB1 (0.45) | ITGB1ITGA4ITGB7ITGA2L3MBTL1 | |
| SCHEMBL6580118 | 0.88 | ITGB1 (0.52) | ITGB1ITGA4ITGB7L3MBTL1ALDH1A1 | |
| SCHEMBL27541119 | 0.87 | NOS2 (0.43) | ITGB1ITGA4ITGB7ITGA2NOS2 | |
| SCHEMBL27541117 | 0.87 | NOS2 (0.43) | ITGB1ITGA4ITGB7ITGA2NOS2 | |
| SCHEMBL7432342 | 0.86 | L3MBTL1 (0.64) | ITGB1ITGA4ITGB7ITGA2L3MBTL1 | |
| SCHEMBL6639882 | 0.85 | ITGB1 (0.60) | ITGB1ITGA4ITGB7ITGA2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100369888-C | N-alkanoylphenylalanine derivatives | HOFFMANN LA ROCHE (CH) | 2008-02-20 | — | — | CN | disclosed |
| CN-1281430-A | N-alkanoylphenylalanine derivatives | HOFFMANN LA ROCHE (CH) | 2001-01-24 | — | — | CN | disclosed |
| EP-1005445-A1 | N-ALKANOYLPHENYLALANINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2000-06-07 | — | — | EP | disclosed |
| WO-1999010312-A1 | N-ALKANOYLPHENYLALANINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 1999-03-04 | — | — | WO | disclosed |