Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | ABL1 | P00519 | 5/20 | 0.54 |
| ▸ | SRC | P12931 | 5/20 | 0.54 |
| ▸ | NPC1 | O15118 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.51 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.49 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7429153 | 0.88 | MEN1 (0.49) | RAB9AMAPTABL1SRCNPC1 | |
| SCHEMBL7479019 | 0.86 | RAB9A (0.61) | RAB9AMAPTTP53ABL1SRC | |
| SCHEMBL7427489 | 0.80 | MEN1 (0.58) | RAB9AMAPTTP53ABL1SRC | |
| SCHEMBL7476339 | 0.78 | MAPT (0.67) | RAB9AMAPTTP53ABL1SRC | |
| SCHEMBL7481013 | 0.78 | MAPT (0.63) | RAB9AMAPTTP53ABL1SRC | |
| SCHEMBL7477611 | 0.77 | KMT2A (0.61) | RAB9AMAPTABL1SRCNPC1 | |
| SCHEMBL7480423 | 0.76 | MAPT (0.66) | RAB9AMAPTTP53ABL1SRC | |
| SCHEMBL7426341 | 0.76 | MEN1 (0.59) | RAB9AMAPTTP53ABL1SRC | |
| SCHEMBL7475712 | 0.74 | MEN1 (0.50) | RAB9AMAPTTP53ABL1SRC | |
| SCHEMBL7478376 | 0.73 | MAPT (0.65) | RAB9AMAPTTP53ABL1SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999020617-A1 | ANTIINFLAMMATORY THIADIAZOLYL UREAS WHICH ACT AS LFA-1 AND MAC-1 INHIBITORS | ACTIVE BIOTECH AB (SE) | 1999-04-29 | — | — | WO | claimed |