Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 1/20 | 0.47 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL742006 | 0.83 | DDB1 (0.43) | DDB1CRBNALDH1A1CA12CA1 | |
| SCHEMBL21504116 | 0.80 | ALDH1A1 (0.45) | DDB1CRBNALDH1A1CA12CA1 | |
| SCHEMBL743375 | 0.79 | DDB1 (0.42) | DDB1CRBNALDH1A1CA12CA1 | |
| SCHEMBL21504136 | 0.76 | DDB1 (0.47) | DDB1CRBNALDH1A1CA12CA1 | |
| SCHEMBL5902814 | 0.75 | DDB1 (0.44) | DDB1CRBNALDH1A1 | |
| SCHEMBL23460656 | 0.75 | ALDH1A1 (0.53) | DDB1CRBNALDH1A1CA12CA1 | |
| SCHEMBL741732 | 0.75 | ALDH1A1 (0.51) | DDB1CRBNALDH1A1CA12CA1 | |
| SCHEMBL2542693 | 0.75 | DDB1 (0.54) | DDB1CRBNALDH1A1CA12CA1 | |
| SCHEMBL741795 | 0.74 | DDB1 (0.51) | DDB1CRBNALDH1A1CA12CA1 | |
| SCHEMBL15114679 | 0.74 | ALDH1A1 (0.51) | DDB1CRBNALDH1A1MAPK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2431370-A1 | Monoacylated 1,2-diaminocycloalkanes | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2012-03-21 | — | — | EP | disclosed |
| US-7935824-B2 | Ethylenediamine derivatives | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2011-05-03 | — | — | US | disclosed |