Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | SNCA | P37840 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.43 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TYMS | P04818 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL74973 | 0.92 | L3MBTL1 (0.55) | ALDH1A1KMT2AL3MBTL1BCHEGAA | |
| SCHEMBL31241181 | 0.92 | L3MBTL1 (0.55) | ALDH1A1KMT2AL3MBTL1BCHEGAA | |
| Ethylene Glycol SCHEMBL8989789 | 0.87 | L3MBTL1 (0.51) | ALDH1A1KMT2AL3MBTL1BCHEGAA | |
| Phthalimide SCHEMBL11427744 | 0.83 | L3MBTL1 (0.48) | ALDH1A1KMT2AL3MBTL1BCHEGAA | |
| SCHEMBL14605580 | 0.81 | L3MBTL1 (0.49) | ALDH1A1KMT2AL3MBTL1BCHEGAA | |
| SCHEMBL8995177 | 0.80 | ALDH1A1 (0.62) | ALDH1A1KMT2AL3MBTL1BCHEGAA | |
| Phthalic Anhydride SCHEMBL27989378 | 0.80 | ALDH1A1 (0.61) | ALDH1A1KMT2AGLAALOX15TDP1 | |
| SCHEMBL5905149 | 0.79 | BCHE (0.47) | ALDH1A1KMT2AGLAL3MBTL1BCHE | |
| Phthalic Anhydride SCHEMBL28455726 | 0.78 | ALDH1A1 (0.59) | ALDH1A1KMT2AGLAALOX15TDP1 | |
| SCHEMBL18485418 | 0.77 | ALDH1A1 (0.56) | ALDH1A1KMT2AL3MBTL1ALOX15TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4562263-A | HYPOTENSIVE AND HYDERTENSIVE AGENTS, ANTIDEPRESSANTS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1985-12-31 | — | — | US | disclosed |
| EP-0128684-A1 | Process for producing 3-(3,4-dihydroxyphenyl) serine | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1984-12-19 | — | — | EP | disclosed |