Phthalimide

Phthalimide

SCHEMBL11427744

CCOC(=O)N1C(=O)c2ccccc2C1=O.O=C1NC(=O)c2ccccc21

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.48
IDO1 P14902 1/20 0.48
TDO2 P48775 1/20 0.48
GSK3B P49841 1/20 0.47
ALDH1A1 P00352 5/20 0.46
KDM4E B2RXH2 4/20 0.46
KMT2A Q03164 2/20 0.46
MEN1 O00255 1/20 0.46
AGTR1 P30556 1/20 0.46
BCHE P06276 1/20 0.45
GAA P10253 5/20 0.44
APP P05067 1/20 0.43
MAPT P10636 1/20 0.43
SNCA P37840 1/20 0.43
CYP1A2 P05177 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.42
TSPO P30536 1/20 0.42
CASP3 P42574 1/20 0.42
CASP2 P42575 1/20 0.42
CASP7 P55210 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL74973 0.90 L3MBTL1 (0.55) L3MBTL1ALDH1A1KMT2ABCHEGAA
SCHEMBL31241181 0.90 L3MBTL1 (0.55) L3MBTL1ALDH1A1KMT2ABCHEGAA
Ethylene Glycol SCHEMBL8989789 0.85 L3MBTL1 (0.51) L3MBTL1ALDH1A1KDM4EKMT2AMEN1
Phthalic Anhydride SCHEMBL7429661 0.83 ALDH1A1 (0.55) L3MBTL1ALDH1A1KMT2ABCHEGAA
Phthalimide SCHEMBL10495296 0.80 GSK3B (0.54) IDO1TDO2GSK3BALDH1A1KDM4E
SCHEMBL14605580 0.79 L3MBTL1 (0.49) L3MBTL1ALDH1A1KDM4EKMT2AMEN1
SCHEMBL8995177 0.79 ALDH1A1 (0.62) L3MBTL1ALDH1A1KMT2ABCHEGAA
Phthalimide SCHEMBL7590940 0.79 ALOX15 (0.52) IDO1TDO2GSK3BALDH1A1KDM4E
Malonic Acid Diethyl Ester SCHEMBL27904592 0.79 CYP1A2 (0.52) IDO1TDO2GSK3BALDH1A1KDM4E
Diethyl Phthalate SCHEMBL27518710 0.78 TSHR (0.70) L3MBTL1IDO1TDO2GSK3BALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4224441-A Derivatives of 7-aminocephalosporanic acid TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1980-09-23 US disclosed