Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | TNF | P01375 | 4/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.50 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.50 |
| ▸ | NAMPT | P43490 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7433345 | 0.81 | KDM4E (0.83) | ALOX15KDM4ETSHRSIRT1MEN1 | |
| SCHEMBL7997184 | 0.81 | KDM4E (0.68) | ALOX15KDM4ETSHRSIRT1KMT2A | |
| SCHEMBL9850744 | 0.81 | TNF (0.51) | KDM4ETNFSMN1; SMN2 | |
| SCHEMBL9850887 | 0.81 | TNF (0.46) | ALOX15KDM4ETNFNAMPT | |
| SCHEMBL22291829 | 0.79 | KDM4E (0.60) | ALOX15KDM4ETSHRSIRT1MEN1 | |
| SCHEMBL29531631 | 0.79 | KDM4E (0.60) | ALOX15KDM4ETSHRSIRT1MEN1 | |
| SCHEMBL7424373 | 0.78 | KMT2A (0.63) | TSHRMEN1KMT2ATNFALDH1A1 | |
| SCHEMBL18030756 | 0.78 | DRD2 (0.60) | ALOX15KDM4ETSHRSIRT1KMT2A | |
| SCHEMBL29532002 | 0.78 | DRD2 (0.60) | ALOX15KDM4ETSHRSIRT1KMT2A | |
| SCHEMBL5195087 | 0.77 | TNF (0.47) | ALOX15KDM4ETNFNAMPTDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0375451-A2 | Compounds having a renin-inhibiting activity | BEECHAM GROUP PLC (GB) | 1990-06-27 | — | — | EP | disclosed |