Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | CTSG | P08311 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28431266 | 0.87 | SMN1; SMN2 (0.47) | POLBMAPTKMT2ACYP1A2CHRM2 | |
| SCHEMBL7435872 | 0.85 | POLB (0.44) | POLBMAPTKMT2ACYP1A2CHRM2 | |
| SCHEMBL7439007 | 0.84 | ELANE (0.41) | ELANEMAPTKMT2ALMNAGSK3B | |
| SCHEMBL7446353 | 0.83 | GSK3B (0.43) | KMT2ACYP1A2CYP2D6LMNAGSK3B | |
| SCHEMBL28430986 | 0.82 | POLB (0.53) | POLBMAPTKMT2ACYP1A2CHRM2 | |
| SCHEMBL5552878 | 0.78 | POLB (0.50) | POLBMAPTKMT2ACYP1A2CHRM2 | |
| SCHEMBL7435421 | 0.75 | POLB (0.40) | POLBMAPTKMT2ACYP1A2CHRM2 | |
| SCHEMBL7435972 | 0.75 | HTR2A (0.42) | POLBMAPTKMT2ACYP1A2CHRM2 | |
| SCHEMBL7392784 | 0.73 | POLB (0.39) | POLBMAPTKMT2ACYP1A2CHRM2 | |
| SCHEMBL8387279 | 0.72 | ELANE (0.35) | ELANEMAPTKMT2ALMNACTSG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5891899-A | Pharmaceutical xanthene compounds | ELI LILLY AND COMPANY LIMITED (GB) | 1999-04-06 | — | — | US | disclosed |
| EP-0849263-A2 | Pharmaceutical substituted propanoic acid derivatives | ELI LILLY AND COMPANY LIMITED (GB) | 1998-06-24 | — | — | EP | disclosed |