Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.37 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
| ▸ | CTSG | P08311 | 1/20 | 0.36 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.36 |
| ▸ | CMA1 | P23946 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7430490 | 0.83 | POLB (0.41) | GSK3BMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL7436707 | 0.82 | GSK3B (0.43) | GSK3BMEN1KMT2AATMCA1 | |
| SCHEMBL4397336 | 0.79 | ATM (0.52) | MEN1KMT2ACYP2C9ATMLMNA | |
| SCHEMBL28431266 | 0.70 | SMN1; SMN2 (0.47) | MEN1KMT2AATMALDH1A1LMNA | |
| SCHEMBL28438194 | 0.69 | CYP2C9 (0.45) | MEN1KMT2ACYP2C9ATMLMNA | |
| SCHEMBL5552878 | 0.68 | POLB (0.50) | MEN1KMT2AATMLMNAL3MBTL1 | |
| SCHEMBL7435872 | 0.67 | POLB (0.44) | MEN1KMT2ACYP2C9MAPK1ALDH1A1 | |
| SCHEMBL9242929 | 0.67 | GRM2 (0.56) | MEN1KMT2ACYP2C9ATMLMNA | |
| SCHEMBL9016791 | 0.67 | ATM (0.49) | MEN1KMT2ACYP2C9ATMLMNA | |
| SCHEMBL29591768 | 0.67 | CYP2C9 (0.49) | MEN1KMT2ACYP2C9ATMLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5891899-A | Pharmaceutical xanthene compounds | ELI LILLY AND COMPANY LIMITED (GB) | 1999-04-06 | — | — | US | disclosed |
| EP-0849263-A2 | Pharmaceutical substituted propanoic acid derivatives | ELI LILLY AND COMPANY LIMITED (GB) | 1998-06-24 | — | — | EP | disclosed |