Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | CTSG | P08311 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CMA1 | P23946 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.35 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.35 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.35 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8387279 | 0.86 | ELANE (0.35) | ELANEKMT2ACTSGALDH1A1SMN1; SMN2 | |
| SCHEMBL7430490 | 0.84 | POLB (0.41) | ELANEKMT2AGSK3BCTSGALDH1A1 | |
| SCHEMBL7436707 | 0.83 | GSK3B (0.43) | KMT2AGSK3BCTSGALDH1A1LMNA | |
| SCHEMBL7431986 | 0.73 | HDAC3 (0.39) | KMT2AALDH1A1LMNAMAPTBCHE | |
| SCHEMBL7394411 | 0.73 | BCHE (0.35) | KMT2AALDH1A1SMN1; SMN2BCHEKDM4E | |
| SCHEMBL10275760 | 0.72 | GSK3B (0.53) | ELANEKMT2AGSK3BALDH1A1SMN1; SMN2 | |
| SCHEMBL14750335 | 0.72 | BCHE (0.43) | KMT2AALDH1A1LMNAMAPTBCHE | |
| SCHEMBL9246765 | 0.72 | BCHE (0.47) | KMT2AALDH1A1LMNAMAPTBCHE | |
| Hydrochloric Acid SCHEMBL9244137 | 0.71 | BCHE (0.46) | KMT2AALDH1A1LMNAMAPTBCHE | |
| SCHEMBL28431266 | 0.70 | SMN1; SMN2 (0.47) | KMT2AALDH1A1SMN1; SMN2LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5891899-A | Pharmaceutical xanthene compounds | ELI LILLY AND COMPANY LIMITED (GB) | 1999-04-06 | — | — | US | disclosed |
| EP-0849263-A2 | Pharmaceutical substituted propanoic acid derivatives | ELI LILLY AND COMPANY LIMITED (GB) | 1998-06-24 | — | — | EP | disclosed |