Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7433411 | 0.86 | — | — | |
| SCHEMBL9865115 | 0.83 | HRH4 (0.39) | — | |
| SCHEMBL9828132 | 0.83 | KDM1A (0.44) | — | |
| SCHEMBL9867357 | 0.82 | SCN5A (0.43) | — | |
| SCHEMBL9828417 | 0.82 | KDM1A (0.47) | — | |
| SCHEMBL9867126 | 0.81 | HRH4 (0.47) | — | |
| SCHEMBL7315384 | 0.81 | NPY1R (0.49) | — | |
| SCHEMBL7295398 | 0.81 | — | — | |
| SCHEMBL9771022 | 0.81 | SIGMAR1 (0.43) | SIGMAR1 | |
| SCHEMBL9865960 | 0.80 | SCN5A (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0448765-B1 | Use of guanidine derivatives for the manufacture of a medicament with NPY-antagonistic activity | HEUMANN PHARMA GMBH & CO (DE) | 1994-08-17 | — | — | EP | claimed |
| EP-0448765-A1 | Use of guanidine derivatives for the manufacture of a medicament with NPY-antagonistic activity | HEUMANN PHARMA GMBH & CO (DE) | 1991-10-02 | — | — | EP | claimed |
| EP-0448765-B1 | Use of guanidine derivatives for the manufacture of a medicament with NPY-antagonistic activity | HEUMANN PHARMA GMBH & CO (DE) | 1994-08-17 | — | — | EP | disclosed |
| EP-0448765-A1 | Use of guanidine derivatives for the manufacture of a medicament with NPY-antagonistic activity | HEUMANN PHARMA GMBH & CO (DE) | 1991-10-02 | — | — | EP | disclosed |
| EP-0302896-B1 | N-(W-SUBSTITUTED ALKYL)-N'-[(IMIDAZOLE-4-YL)ALKYL]GUANIDINE | CEDONA PHARMACEUTICALS B.V. (NL) | 1991-08-14 | — | — | EP | disclosed |
| US-5010095-A | Antiallergens, congestive heart failure | CEDONA PHARMACEUTICALS B.V. (NL) | 1991-04-23 | — | — | US | disclosed |