Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.57 |
| ▸ | CTSL | P07711 | 2/20 | 0.55 |
| ▸ | CTSS | P25774 | 1/20 | 0.55 |
| ▸ | CTSK | P43235 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | ACE | P12821 | 1/20 | 0.52 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.52 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.52 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.52 |
| ▸ | MIF | P14174 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7430601 | 1.00 | TACR1 (0.58) | TACR1KMT2AMEN1HCRTR1CTSL | |
| SCHEMBL6430686 | 0.94 | TACR1 (0.56) | TACR1KMT2AMEN1HCRTR1CTSL | |
| SCHEMBL8553442 | 0.90 | ACE (0.61) | TACR1KMT2AMEN1CTSLCTSS | |
| SCHEMBL7434878 | 0.90 | ACE (0.61) | TACR1KMT2AMEN1CTSLCTSS | |
| SCHEMBL7433228 | 0.87 | PKM (0.56) | TACR1KMT2AMEN1HCRTR1CTSL | |
| SCHEMBL7433229 | 0.87 | PKM (0.56) | TACR1KMT2AMEN1HCRTR1CTSL | |
| SCHEMBL27332474 | 0.85 | TACR1 (0.61) | TACR1KMT2AMEN1HCRTR1CTSL | |
| SCHEMBL30841400 | 0.85 | TACR1 (0.61) | TACR1KMT2AMEN1HCRTR1CTSL | |
| SCHEMBL1631176 | 0.84 | KMT2A (0.59) | TACR1KMT2AMEN1HCRTR1TDP1 | |
| SCHEMBL5251038 | 0.84 | TACR1 (0.78) | TACR1KMT2AMEN1HCRTR1CTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640594-A1 | Hydantoin derivative as metalloprotease inhibitor | FUJIREBIO INC. (JP) | 1995-03-01 | — | — | EP | disclosed |