Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 4/20 | 0.61 |
| ▸ | CTSL | P07711 | 2/20 | 0.58 |
| ▸ | CTSS | P25774 | 1/20 | 0.58 |
| ▸ | CTSK | P43235 | 1/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | ITGB2 | P05107 | 2/20 | 0.54 |
| ▸ | ICAM1 | P05362 | 2/20 | 0.54 |
| ▸ | ITGAL | P20701 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | TACR1 | P25103 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | APAF1 | O14727 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | ECE1 | P42892 | 3/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8553442 | 1.00 | ACE (0.61) | ACECTSLCTSSCTSKALOX15 | |
| SCHEMBL6430686 | 0.91 | TACR1 (0.56) | ACECTSLCTSSCTSKALOX15 | |
| SCHEMBL7430608 | 0.90 | TACR1 (0.58) | ACECTSLCTSSCTSKMEN1 | |
| SCHEMBL7430601 | 0.90 | TACR1 (0.58) | ACECTSLCTSSCTSKMEN1 | |
| SCHEMBL1003555 | 0.84 | ACE (0.77) | ACECTSLCTSSCTSKALOX15 | |
| SCHEMBL850438 | 0.84 | ACE (0.77) | ACECTSLCTSSCTSKALOX15 | |
| SCHEMBL29367687 | 0.84 | ACE (0.77) | ACECTSLCTSSCTSKALOX15 | |
| SCHEMBL30976323 | 0.84 | ACE (0.77) | ACECTSLCTSSCTSKALOX15 | |
| SCHEMBL1486167 | 0.84 | ACE (0.77) | ACECTSLCTSSCTSKALOX15 | |
| SCHEMBL7433229 | 0.84 | PKM (0.56) | ACECTSLCTSSCTSKMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6066633-A | PREVENT TISSUE DEGRADATION | ADIR ET COMPAGNIE (FR) | 2000-05-23 | — | — | US | disclosed |