Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | TACR1 | P25103 | 4/20 | 0.55 |
| ▸ | CTSL | P07711 | 2/20 | 0.53 |
| ▸ | CTSS | P25774 | 1/20 | 0.53 |
| ▸ | CTSK | P43235 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 6/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | ACE | P12821 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | MMP2 | P08253 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7433229 | 1.00 | PKM (0.56) | PKMTACR1CTSLCTSSCTSK | |
| SCHEMBL6430686 | 0.93 | TACR1 (0.56) | TACR1CTSLCTSSCTSKSMN1; SMN2 | |
| SCHEMBL7430608 | 0.87 | TACR1 (0.58) | TACR1CTSLCTSSCTSKMAPT | |
| SCHEMBL7430601 | 0.87 | TACR1 (0.58) | TACR1CTSLCTSSCTSKMAPT | |
| SCHEMBL24726483 | 0.84 | CTSL (0.73) | TACR1CTSLCTSSCTSKSMN1; SMN2 | |
| SCHEMBL8553442 | 0.84 | ACE (0.61) | TACR1CTSLCTSSCTSKMAPT | |
| SCHEMBL7434878 | 0.84 | ACE (0.61) | TACR1CTSLCTSSCTSKMAPT | |
| SCHEMBL4842426 | 0.82 | TACR1 (0.55) | TACR1CTSLCTSSCTSKSMN1; SMN2 | |
| SCHEMBL23901489 | 0.81 | TACR1 (0.58) | TACR1CTSLCTSSCTSKSMN1; SMN2 | |
| SCHEMBL25453628 | 0.81 | TACR1 (0.58) | TACR1CTSLCTSSCTSKSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640594-A1 | Hydantoin derivative as metalloprotease inhibitor | FUJIREBIO INC. (JP) | 1995-03-01 | — | — | EP | disclosed |