Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | ACACB | O00763 | 3/20 | 0.40 |
| ▸ | ACACA | Q13085 | 1/20 | 0.40 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 5/20 | 0.38 |
| ▸ | CA1 | P00915 | 5/20 | 0.38 |
| ▸ | CA2 | P00918 | 5/20 | 0.38 |
| ▸ | CA9 | Q16790 | 5/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7430950 | 0.80 | NQO2 (0.47) | CA12CA1CA2CA9MAPT | |
| SCHEMBL16935680 | 0.79 | CKS1B (0.40) | CA12CA1CA2CA9TSHR | |
| SCHEMBL10233014 | 0.77 | ALDH1A1 (0.52) | ACACBALDH1A1TSHRCACNA1B | |
| SCHEMBL7430134 | 0.76 | NOX1 (0.46) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL15862041 | 0.76 | IDO1 (0.40) | CA12CA1CA2CA9LMNA | |
| SCHEMBL22312236 | 0.74 | PPIB (0.43) | DGAT1CA12CA1CA2CA9 | |
| SCHEMBL15584401 | 0.73 | NQO2 (0.43) | CA12CA1CA2CA9MTNR1A | |
| SCHEMBL15283620 | 0.72 | CKS1B (0.50) | CA12CA1MTNR1A | |
| SCHEMBL9363322 | 0.72 | TDP1 (0.49) | CA12CA1CA2CA9 | |
| SCHEMBL28357342 | 0.72 | CKS1B (0.42) | CA12CA1CA2CA9MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000048993-A1 | ARYLAMINOALKYLAMIDES | NOVARTIS AG (CH) | 2000-08-24 | — | — | WO | disclosed |