Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.49 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.49 |
| ▸ | KDM1A | O60341 | 7/20 | 0.48 |
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | APP | P05067 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.44 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13504467 | 0.91 | LTA4H (0.47) | LTA4HMAPK14KDM1AMAOBMAPT | |
| SCHEMBL810075 | 0.91 | LTA4H (0.47) | LTA4HMAPK14KDM1AMAOBMAPT | |
| SCHEMBL29178713 | 0.91 | LTA4H (0.47) | LTA4HMAPK14KDM1AMAOBMAPT | |
| SCHEMBL14259448 | 0.88 | LTA4H (0.47) | LTA4HMAPK14KDM1AMAOBMAPT | |
| SCHEMBL23898522 | 0.87 | APP (0.47) | LTA4HMAPK14KDM1AMAOBMAPT | |
| SCHEMBL30739394 | 0.87 | MAPT (0.49) | LTA4HMAPK14KDM1AMAOBMAPT | |
| SCHEMBL8313819 | 0.87 | LTA4H (0.56) | LTA4HMAPK14MAOBMAPTL3MBTL1 | |
| SCHEMBL3920530 | 0.86 | LTA4H (0.49) | LTA4HMAPK14KDM1AMAOBMAPT | |
| SCHEMBL582711 | 0.83 | FOLH1 (0.51) | L3MBTL1NPC1MRGPRX4PTGER1S1PR5 | |
| SCHEMBL7426704 | 0.81 | PTGES (0.51) | MAPTCYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1117651-A1 | NEW BIS-BENZIMIDAZOLES | Bayer Aktiengesellschaft (DE) | 2001-07-25 | — | — | EP | disclosed |
| WO-2000020401-A1 | NEW BIS-BENZIMIDAZOLES | BAYER AKTIENGESELLSCHAFT (DE) | 2000-04-13 | — | — | WO | disclosed |