Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP26A1 | O43174 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 4/20 | 0.33 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.31 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7435278 | 0.80 | ALDH1A1 (0.36) | ALDH1A1TSHRNR1H4POLBKDM4E | |
| SCHEMBL7440686 | 0.69 | ALDH1A1 (0.38) | ALDH1A1TSHRNR1H4 | |
| SCHEMBL7432817 | 0.68 | ALDH1A1 (0.42) | ALDH1A1TSHRNR1H4POLBKMT2A | |
| SCHEMBL7432156 | 0.68 | ALOX5 (0.47) | CYP1A2CYP2C19KMT2ASMN1; SMN2 | |
| SCHEMBL7437942 | 0.67 | ALDH1A1 (0.43) | ALDH1A1TSHRPOLBKDM4ECYP2C19 | |
| SCHEMBL14833639 | 0.63 | TSHR (0.51) | ALDH1A1TSHRPOLBKDM4EKMT2A | |
| SCHEMBL7441666 | 0.62 | CYP1A2 (0.39) | ALDH1A1TSHRPOLBKDM4ECYP1A2 | |
| SCHEMBL31028133 | 0.61 | ALDH1A1 (0.56) | ALDH1A1TSHRPOLBKDM4ECYP1A2 | |
| SCHEMBL39249 | 0.61 | ALDH1A1 (0.56) | ALDH1A1TSHRPOLBKDM4ECYP1A2 | |
| SCHEMBL12251425 | 0.61 | ALDH1A1 (0.50) | ALDH1A1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5491149-A | VIRICIDES | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-02-13 | — | — | US | disclosed |