Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 5/20 | 0.47 |
| ▸ | MAOB | P27338 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.43 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | RXRA | P19793 | 1/20 | 0.42 |
| ▸ | RXRB | P28702 | 1/20 | 0.42 |
| ▸ | RXRG | P48443 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7430127 | 0.83 | ALOX5 (0.50) | ALOX5MAOBLMNACYP1A2PTGS1 | |
| SCHEMBL7440686 | 0.83 | ALDH1A1 (0.38) | SLC6A2RXRARXRBRXRG | |
| SCHEMBL7435278 | 0.74 | ALDH1A1 (0.36) | CYP1A2CYP2C19MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9129927 | 0.72 | ALOX5 (0.50) | ALOX5LMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL9637755 | 0.70 | MAOB (0.59) | ALOX5MAOBLMNACYP1A2PTGS1 | |
| SCHEMBL9451329 | 0.69 | LMNA (0.61) | MAOBLMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL9634739 | 0.69 | LMNA (0.72) | ALOX5MAOBLMNACYP1A2PTGS1 | |
| SCHEMBL7688711 | 0.69 | LMNA (0.72) | ALOX5MAOBLMNACYP1A2PTGS1 | |
| SCHEMBL27038087 | 0.69 | LMNA (0.72) | ALOX5MAOBLMNACYP1A2PTGS1 | |
| SCHEMBL419050 | 0.68 | APP (0.69) | MAOBLMNACYP1A2PTGS1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5491149-A | VIRICIDES | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-02-13 | — | — | US | disclosed |