Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 3/20 | 0.76 |
| ▸ | RAB9A | P51151 | 6/20 | 0.66 |
| ▸ | NPC1 | O15118 | 5/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.66 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.66 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.66 |
| ▸ | RELA | Q04206 | 3/20 | 0.66 |
| ▸ | TP53 | P04637 | 2/20 | 0.66 |
| ▸ | MAPT | P10636 | 2/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.66 |
| ▸ | GAA | P10253 | 1/20 | 0.65 |
| ▸ | HTT | P42858 | 1/20 | 0.65 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.62 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.62 |
| ▸ | F2 | P00734 | 1/20 | 0.59 |
| ▸ | PLG | P00747 | 1/20 | 0.59 |
| ▸ | PLAT | P00750 | 1/20 | 0.59 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.59 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.59 |
| ▸ | LY96 | Q9Y6Y9 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7344370 | 0.87 | PLAU (1.00) | PLAURAB9ANPC1SMN1; SMN2NFKB1 | |
| SCHEMBL8460943 | 0.84 | RAB9A (0.75) | PLAURAB9ANPC1SMN1; SMN2NFKB1 | |
| SCHEMBL3331071 | 0.79 | RAB9A (0.74) | PLAURAB9ANPC1SMN1; SMN2NFKB1 | |
| SCHEMBL21468516 | 0.79 | NPC1 (0.68) | RAB9ANPC1SMN1; SMN2NFKB1NFKB2 | |
| SCHEMBL13170480 | 0.79 | NPC1 (0.86) | RAB9ANPC1SMN1; SMN2NFKB1NFKB2 | |
| SCHEMBL29669746 | 0.78 | RAB9A (0.76) | PLAURAB9ANPC1SMN1; SMN2NFKB1 | |
| SCHEMBL28256407 | 0.78 | RAB9A (0.76) | PLAURAB9ANPC1SMN1; SMN2NFKB1 | |
| SCHEMBL3783652 | 0.78 | ADRA2A (0.55) | PLAURAB9ANPC1SMN1; SMN2NFKB1 | |
| Hydrochloric Acid SCHEMBL8994029 | 0.78 | F2 (0.71) | PLAURAB9ANPC1F2PLG | |
| SCHEMBL7305449 | 0.77 | ITGB3 (0.92) | PLAUITGB3ITGA2BTMPRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0709370-A1 | Bicyclic compounds useful as platelet aggregation inhibitors | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-05-01 | — | — | EP | claimed |