Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | PRKDC | P78527 | 1/20 | 0.33 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 2/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26344188 | 0.73 | CHEK1 (0.40) | CHEK1ALDH1A1KDM4EHPGDGAA | |
| SCHEMBL4507803 | 0.71 | PARP1 (0.40) | ALDH1A1KDM4EHPGDMAPTSMN1; SMN2 | |
| SCHEMBL4512211 | 0.70 | ALKBH5 (0.41) | ALDH1A1KDM4EHPGDGAAMEN1 | |
| SCHEMBL31190839 | 0.70 | ALKBH5 (0.41) | ALDH1A1KDM4EHPGDGAAMEN1 | |
| Hydrochloric Acid SCHEMBL27528480 | 0.69 | ALKBH5 (0.40) | ALDH1A1KDM4EHPGDGAAMEN1 | |
| SCHEMBL21651191 | 0.68 | GPR3 (0.38) | ALDH1A1KDM4EHPGDMAPTCYP1A2 | |
| SCHEMBL19914101 | 0.65 | CYP1A2 (0.47) | ALDH1A1KDM4EHPGDACHEGAA | |
| SCHEMBL15829525 | 0.64 | PARP1 (0.47) | ALDH1A1KDM4EHPGDGAAMEN1 | |
| SCHEMBL2877514 | 0.64 | CYP3A4 (0.54) | ALDH1A1KDM4EHPGDMAPTSMN1; SMN2 | |
| SCHEMBL30183455 | 0.64 | CYP3A4 (0.54) | ALDH1A1KDM4EHPGDMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0357417-A1 | Lactam derivatives | GLAXO GROUP LIMITED (GB) | 1990-03-07 | — | — | EP | disclosed |