SCHEMBL26344188

SCHEMBL26344188

c1cc2ccc3ccn4c5cccnc5c(c1)c2c34

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHEK1 O14757 1/20 0.40
LMNA P02545 2/20 0.39
CCR1 P32246 5/20 0.39
CCR8 P51685 5/20 0.39
CCR5 P51681 3/20 0.39
CYP3A4 P08684 3/20 0.39
KDM4E B2RXH2 2/20 0.39
MMP2 P08253 2/20 0.39
TSHR P16473 2/20 0.39
MAPT P10636 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
GMNN O75496 1/20 0.39
TP53 P04637 1/20 0.39
HSP90AA1 P07900 1/20 0.39
CYP2D6 P10635 1/20 0.39
MMP9 P14780 1/20 0.39
ALOX15 P16050 1/20 0.39
NFKB1 P19838 1/20 0.39
MMP8 P22894 1/20 0.39
THPO P40225 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26344199 0.79 CCR1 (0.43) CHEK1LMNACCR1CCR8CCR5
SCHEMBL19914101 0.78 CYP1A2 (0.47) CYP3A4KDM4ETSHRMAPTHIF1A
SCHEMBL26343896 0.75 LMNA (0.38) LMNACCR1CCR8CCR5CYP3A4
SCHEMBL26344209 0.75 CHEK1 (0.37) CHEK1LMNAKDM4ETSHRMAPT
SCHEMBL26344203 0.74 CHEK1 (0.36) CHEK1LMNAKDM4EMAPTHSP90AA1
SCHEMBL7430810 0.73 CHEK1 (0.40) CHEK1CYP3A4KDM4EMMP2TSHR
SCHEMBL21917612 0.71 KDM4E (0.46) CHEK1LMNACCR1CCR8CCR5
SCHEMBL21298303 0.71 CYP3A4 (0.38) CHEK1LMNACCR1CCR8CCR5
SCHEMBL4507803 0.68 PARP1 (0.40) LMNACCR1CCR8CCR5CYP3A4
SCHEMBL4859283 0.68 TSHR (0.47) LMNACCR1CCR8CCR5CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230250118-A1 ELECTROLUMINESCENT MATERIAL AND DEVICE THEREOF Beijing Summer Sprout Technology Co., Ltd. (CN) 2023-08-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230250118-A1 ELECTROLUMINESCENT MATERIAL AND DEVICE THEREOF CRY1, LEF1, PIEZO1 CHEK1 3606/4885LMNA 1501/4885CCR1 2958/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.