Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 2/20 | 0.39 |
| ▸ | ACE | P12821 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | GSK3A | P49840 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7442598 | 0.85 | ENPP2 (0.40) | ENPP2ACEHTTSMN1; SMN2LMNA | |
| SCHEMBL7438165 | 0.84 | ENPP2 (0.40) | ENPP2ACEHTTSMN1; SMN2LMNA | |
| SCHEMBL7430867 | 0.78 | ENPP2 (0.42) | ENPP2ACEHTTSMN1; SMN2LMNA | |
| SCHEMBL7428792 | 0.76 | CYP2D6 (0.45) | ENPP2ACEKMT2ACYP2D6CYP2C19 | |
| SCHEMBL7442589 | 0.76 | ENPP2 (0.40) | ENPP2ACEHTTSMN1; SMN2LMNA | |
| SCHEMBL6792682 | 0.69 | TSHR (0.45) | ACEHTTSMN1; SMN2LMNAKMT2A | |
| SCHEMBL15743860 | 0.69 | SMN1; SMN2 (0.51) | ACEHTTSMN1; SMN2LMNAKMT2A | |
| SCHEMBL7428787 | 0.68 | KMT2A (0.45) | ENPP2ACELMNAKMT2ACYP2D6 | |
| SCHEMBL24742415 | 0.66 | ENPP2 (0.35) | ENPP2 | |
| SCHEMBL15550729 | 0.66 | MEN1 (0.36) | ENPP2HTTSMN1; SMN2LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640594-A1 | Hydantoin derivative as metalloprotease inhibitor | FUJIREBIO INC. (JP) | 1995-03-01 | — | — | EP | disclosed |