Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 2/20 | 0.40 |
| ▸ | ACE | P12821 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7442598 | 0.87 | ENPP2 (0.40) | ENPP2ACEHTTSMN1; SMN2POLB | |
| SCHEMBL7430876 | 0.84 | ENPP2 (0.39) | ENPP2ACEHTTSMN1; SMN2POLB | |
| SCHEMBL7428792 | 0.79 | CYP2D6 (0.45) | ENPP2ACEPOLBCYP2D6CYP2C9 | |
| SCHEMBL7430867 | 0.78 | ENPP2 (0.42) | ENPP2ACEHTTSMN1; SMN2POLB | |
| SCHEMBL7438154 | 0.76 | ENPP2 (0.39) | ENPP2ACEHTTSMN1; SMN2POLB | |
| SCHEMBL7442589 | 0.75 | ENPP2 (0.40) | ENPP2ACEHTTSMN1; SMN2POLB | |
| SCHEMBL7428456 | 0.67 | PLA2G10 (0.45) | ENPP2ACESMN1; SMN2POLBALDH1A1 | |
| SCHEMBL7426522 | 0.66 | MAPT (0.43) | ENPP2HTTSMN1; SMN2POLBKMT2A | |
| SCHEMBL6792682 | 0.66 | TSHR (0.45) | ACEHTTSMN1; SMN2POLBLMNA | |
| SCHEMBL15743860 | 0.66 | SMN1; SMN2 (0.51) | ACEHTTSMN1; SMN2POLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640594-A1 | Hydantoin derivative as metalloprotease inhibitor | FUJIREBIO INC. (JP) | 1995-03-01 | — | — | EP | disclosed |