Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ACE | P12821 | 10/20 | 0.44 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MME | P08473 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7426522 | 0.88 | MAPT (0.43) | POLBKMT2AENPP2NPSR1 | |
| SCHEMBL7436003 | 0.85 | HDAC6 (0.42) | POLBKMT2AACEENPP2 | |
| SCHEMBL7432645 | 0.85 | ENPP2 (0.47) | CYP2D6CYP2C19POLBCYP2C9KMT2A | |
| SCHEMBL7428456 | 0.84 | PLA2G10 (0.45) | POLBACEENPP2NPSR1 | |
| SCHEMBL7445702 | 0.81 | ACHE (0.40) | POLBKMT2AENPP2NPSR1 | |
| SCHEMBL7435811 | 0.79 | ACHE (0.41) | CYP2D6CYP2C19POLBCYP2C9KMT2A | |
| SCHEMBL7438165 | 0.79 | ENPP2 (0.40) | CYP2D6CYP2C19POLBCYP2C9KMT2A | |
| SCHEMBL7446529 | 0.78 | ACE (0.41) | POLBKMT2AACENPSR1 | |
| SCHEMBL7440468 | 0.78 | POLB (0.37) | POLBKMT2ANPSR1 | |
| SCHEMBL7440735 | 0.77 | L3MBTL1 (0.42) | KMT2AENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640594-A1 | Hydantoin derivative as metalloprotease inhibitor | FUJIREBIO INC. (JP) | 1995-03-01 | — | — | EP | disclosed |