Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 4/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.33 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.30 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.30 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.30 |
| ▸ | ITGAL | P20701 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8309740 | 0.84 | PKM (0.36) | PKMTSHRMAOBCYP19A1ABCG2 | |
| SCHEMBL9768971 | 0.77 | PKM (0.38) | PKMTSHRMAOBCYP19A1ABCG2 | |
| SCHEMBL9724429 | 0.77 | PKM (0.38) | PKMTSHRMAOBCYP19A1ABCG2 | |
| SCHEMBL295321 | 0.77 | PKM (0.38) | PKMTSHRMAOBCYP19A1ABCG2 | |
| Hydrochloric Acid SCHEMBL15054537 | 0.75 | PKM (0.37) | PKMTSHRMAOBCYP19A1ABCG2 | |
| SCHEMBL9043334 | 0.75 | AKR1B1 (0.40) | PKMTSHRMAOBCYP19A1 | |
| SCHEMBL9834913 | 0.75 | PKM (0.34) | PKMTSHR | |
| SCHEMBL293833 | 0.74 | PKM (0.36) | PKMTSHRMAOBCYP19A1ABCG2 | |
| SCHEMBL3430194 | 0.73 | PKM (0.37) | PKMTSHRMAOBCYP19A1 | |
| SCHEMBL2004582 | 0.73 | TSHR (0.42) | PKMTSHRMAOBCYP19A1ABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0651765-A1 | ANALOGS OF PTH AND PTHRP, THEIR SYNTHESIS AND USE FOR THE TREATMENT OF OSTEOPOROSIS | SYNTEX (U.S.A.) INC. (US) | 1995-05-10 | — | — | EP | claimed |
| WO-1994001460-A1 | ANALOGS OF PTH AND PTHRP, THEIR SYNTHESIS AND USE FOR THE TREATMENT OF OSTEOPOROSIS | SYNTEX (U.S.A.) INC. (US) | 1994-01-20 | — | — | WO | claimed |