Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.33 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.33 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.33 |
| ▸ | ITGAL | P20701 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 4/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | CRHBP | P24387 | 2/20 | 0.30 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9724429 | 0.81 | PKM (0.38) | PKMTSHRABCG2ITGB2ICAM1 | |
| SCHEMBL295321 | 0.81 | PKM (0.38) | PKMTSHRABCG2ITGB2ICAM1 | |
| SCHEMBL16263333 | 0.80 | PKM (0.35) | PKMTSHRABCG2ITGB2ICAM1 | |
| Hydrochloric Acid SCHEMBL15054537 | 0.79 | PKM (0.37) | PKMTSHRABCG2ITGB2ICAM1 | |
| SCHEMBL8309740 | 0.78 | PKM (0.36) | PKMTSHRABCG2ITGB2ICAM1 | |
| SCHEMBL293833 | 0.78 | PKM (0.36) | PKMTSHRABCG2ITGB2ICAM1 | |
| SCHEMBL9768795 | 0.77 | HTR7 (0.35) | PKMTSHRABCG2ITGB2ICAM1 | |
| SCHEMBL4564855 | 0.77 | TSHR (0.35) | PKMTSHRABCG2ITGB2ICAM1 | |
| SCHEMBL11004170 | 0.77 | ADRA2A (0.47) | MAOBCYP19A1KMT2AADRA2ASMN1; SMN2 | |
| SCHEMBL7430943 | 0.77 | PKM (0.39) | PKMTSHRABCG2ITGB2ICAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0040506-B1 | REACTIVE POLYMER AND PROCESS FOR THE PREPARATION THEREOF | TEIJIN LIMITED (JP) | 1986-08-20 | — | — | EP | claimed |
| US-5030625-A | Applying to phytopathogen | SANDOZ LTD. (CH) | 1991-07-09 | — | — | US | disclosed |
| EP-0191269-B1 | NOVEL HOMOPROPARGYLAMINES | SANDOZ AG (CH) | 1991-03-06 | — | — | EP | disclosed |
| EP-0157267-B1 | SUBSTITUTED BENZOPYRANS, PROCESS FOR THEIR PREPARATION AND THEIR USE IN MEDICINES | BAYER AG (DE) | 1988-11-23 | — | — | EP | disclosed |
| US-4684661-A | Anti-fungal homopropargylamines, compositions, and method of use therefor | SANDOZ LTD. (CH) | 1987-08-04 | — | — | US | disclosed |
| EP-0074611-B1 | METHOD FOR PRODUCTION OF CEPHALOSPORIN COMPOUNDS | Takeda Chemical Industries, Ltd. (JP) | 1987-07-22 | — | — | EP | disclosed |
| US-4659737-A | Substituted aminomethyl benzopyrans having anti-hypertensive activities | BAYER AKTIENGESELLSCHAFT (DE) | 1987-04-21 | — | — | US | disclosed |
| EP-0191269-A2 | Novel homopropargylamines | SANDOZ AG (CH) | 1986-08-20 | — | — | EP | disclosed |
| EP-0114374-B1 | SUBSTITUTED 4-AMINOMETHYLENE CHROMANS OR CHROMENES, PROCESS FOR THEIR PREPARATION AND THEIR USE IN MEDICINES | BAYER AG (DE) | 1986-07-23 | — | — | EP | disclosed |
| US-4563458-A | CIRCULATORY SYSTEM DISORDERS | BAYER AKTIENGESELLSCHAFT (DE) | 1986-01-07 | — | — | US | disclosed |
| EP-0157267-A2 | Substituted benzopyrans, process for their preparation and their use in medicines | BAYER AG (DE) | 1985-10-09 | — | — | EP | disclosed |
| EP-0114374-A1 | Substituted 4-aminomethylene chromans or chromenes, process for their preparation and their use in medicines | BAYER AG (DE) | 1984-08-01 | — | — | EP | disclosed |
| US-4382951-A | FUNGICIDES | SANDOZ LTD. (CH) | 1983-05-10 | — | — | US | disclosed |
| EP-0051824-A2 | Improvement in the method for producing 7-aminocephem compounds | Takeda Chemical Industries, Ltd. (JP) | 1982-05-19 | — | — | EP | disclosed |