Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 17/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 2/20 | 0.44 |
| ▸ | PDE1A | P54750 | 2/20 | 0.44 |
| ▸ | PDE1B | Q01064 | 2/20 | 0.44 |
| ▸ | PDE1C | Q14123 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | PDE2A | O00408 | 1/20 | 0.44 |
| ▸ | PDE6D | O43924 | 1/20 | 0.44 |
| ▸ | PDE9A | O76083 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | PDE6A | P16499 | 1/20 | 0.44 |
| ▸ | PDE6G | P18545 | 1/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6934359 | 0.80 | PDE5A (0.48) | PDE5A | |
| SCHEMBL7447937 | 0.77 | PDE5A (0.47) | PDE5APDE1APDE2APDE9ALMNA | |
| SCHEMBL7446947 | 0.77 | ALDH1A1 (0.46) | PDE5AALDH1A1KDM4EKMT2AUSP2 | |
| SCHEMBL6332419 | 0.68 | PDE5A (0.62) | PDE5AALDH1A1KDM4EKMT2APDE1A | |
| SCHEMBL5233011 | 0.67 | CNR1 (0.40) | ALDH1A1KDM4EKMT2AMEN1LMNA | |
| SCHEMBL6198487 | 0.67 | PDE5A (0.65) | PDE5AALDH1A1KDM4EKMT2AUSP2 | |
| SCHEMBL6332612 | 0.66 | PDE5A (0.61) | PDE5AALDH1A1KDM4EKMT2AUSP2 | |
| SCHEMBL5248537 | 0.65 | GUSB (0.43) | PDE5AALDH1A1KDM4EKMT2APDE1A | |
| SCHEMBL6202064 | 0.65 | PDE5A (0.63) | PDE5AALDH1A1KDM4EKMT2AUSP2 | |
| SCHEMBL6330442 | 0.65 | PDE5A (0.74) | PDE5AALDH1A1KDM4EKMT2AUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993006104-A1 | PYRAZOLOPYRIMIDINONE ANTIANGINAL AGENTS | PFIZER LIMITED (GB) | 1993-04-01 | — | — | WO | disclosed |