Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | CASP7 | P55210 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | PDE5A | O76074 | 18/20 | 0.46 |
| ▸ | PDE1A | P54750 | 4/20 | 0.45 |
| ▸ | PDE1B | Q01064 | 4/20 | 0.45 |
| ▸ | PDE1C | Q14123 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 2/20 | 0.45 |
| ▸ | PDE2A | O00408 | 1/20 | 0.45 |
| ▸ | PDE6D | O43924 | 1/20 | 0.45 |
| ▸ | PDE9A | O76083 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7950670 | 0.80 | KDM4E (0.46) | KMT2AKDM4EPDE5AMEN1PDE6C | |
| SCHEMBL6202064 | 0.79 | PDE5A (0.63) | ALDH1A1KMT2AKDM4EHSD17B10GLA | |
| SCHEMBL7430980 | 0.77 | PDE5A (0.45) | ALDH1A1KMT2AKDM4EHSD17B10GLA | |
| SCHEMBL1872915 | 0.76 | PDE5A (0.58) | ALDH1A1KMT2AHSD17B10PDE5APDE1A | |
| SCHEMBL7360293 | 0.74 | ALDH1A1 (0.39) | ALDH1A1KMT2AKDM4EHSD17B10PDE5A | |
| Potassium Ion SCHEMBL7465463 | 0.74 | PDE5A (0.57) | ALDH1A1KMT2AKDM4EHSD17B10GLA | |
| SCHEMBL6249380 | 0.74 | PDE5A (0.42) | ALDH1A1KMT2AKDM4EPDE5APDE1A | |
| SCHEMBL7964905 | 0.73 | PDE5A (0.38) | ALDH1A1KMT2AKDM4EPDE5APDE1A | |
| SCHEMBL17545115 | 0.73 | PDE5A (0.68) | PDE5APDE1APDE2APDE9APDE4A | |
| SCHEMBL7019550 | 0.72 | PDE5A (0.46) | KMT2AHSD17B10PDE5APDE1APDE1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001087888-A1 | PYRAZOLOPYRIMIDINONE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE | SK CHEMICALS CO., LTD. (KR) | 2001-11-22 | — | — | WO | disclosed |