Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | ECE1 | P42892 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5354676 | 0.86 | KMT2A (0.53) | LMNAKMT2AMEN1CYP1A2CYP3A4 | |
| SCHEMBL27967479 | 0.81 | ALDH1A1 (0.49) | LMNAKMT2AMEN1CYP1A2CYP3A4 | |
| SCHEMBL5358945 | 0.81 | LMNA (0.57) | LMNAKMT2AMEN1CYP1A2CYP3A4 | |
| SCHEMBL5365608 | 0.80 | KMT2A (0.61) | LMNAKMT2AMEN1CYP1A2CYP3A4 | |
| SCHEMBL1106964 | 0.80 | HDAC1 (0.62) | LMNAKMT2AMEN1CYP1A2CYP3A4 | |
| SCHEMBL13274593 | 0.77 | SREBF2 (0.62) | LMNAKMT2AMEN1CYP3A4HDAC1 | |
| SCHEMBL13274592 | 0.77 | SREBF2 (0.62) | LMNAKMT2AMEN1CYP3A4HDAC1 | |
| SCHEMBL13281520 | 0.77 | SREBF2 (0.62) | LMNAKMT2AMEN1CYP3A4HDAC1 | |
| SCHEMBL10894691 | 0.76 | LMNA (0.65) | LMNAKMT2AMEN1CYP3A4THRB | |
| SCHEMBL6860757 | 0.76 | HDAC1 (0.57) | LMNAKMT2AMEN1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0370821-A2 | 1,4-dihydropyridine derivatives | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1990-05-30 | — | — | EP | disclosed |