Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | CRHBP | P24387 | 1/20 | 0.56 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL169682 | 0.87 | KMT2A (0.55) | POLBGAAALDH1A1MEN1KMT2A | |
| SCHEMBL9038839 | 0.86 | RAB9A (0.59) | POLBGAAALDH1A1MEN1KMT2A | |
| SCHEMBL3293477 | 0.85 | ALDH1A1 (0.55) | GAAALDH1A1MEN1KMT2ARAB9A | |
| Methyl Alcohol SCHEMBL11374946 | 0.84 | MEN1 (0.55) | GAAALDH1A1MEN1KMT2ARAB9A | |
| SCHEMBL29719546 | 0.84 | KMT2A (0.56) | POLBGAAALDH1A1MEN1KMT2A | |
| SCHEMBL29530525 | 0.83 | GRM5 (0.49) | POLBGAAALDH1A1MEN1KMT2A | |
| SCHEMBL564719 | 0.83 | GRM5 (0.49) | POLBGAAALDH1A1MEN1KMT2A | |
| SCHEMBL20653314 | 0.82 | ROCK2 (0.46) | POLBGAAALDH1A1MEN1KMT2A | |
| SCHEMBL3287615 | 0.81 | CYP19A1 (0.42) | GAAALDH1A1MEN1KMT2ARAB9A | |
| SCHEMBL3164417 | 0.80 | MEN1 (0.48) | ALDH1A1MEN1KMT2ARAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0359547-B1 | Pyridine compounds and pharmaceutical use thereof | YOSHITOMI PHARMACEUTICAL (JP) | 1996-01-24 | — | — | EP | disclosed |
| EP-0558094-A1 | Pyridine compounds for treating amnesia | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1993-09-01 | — | — | EP | disclosed |
| US-5001137-A | Pyridine compounds and pharmaceutical use thereof | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1991-03-19 | — | — | US | disclosed |
| EP-0359547-A1 | Pyridine compounds and pharmaceutical use thereof | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1990-03-21 | — | — | EP | disclosed |