SCHEMBL502785

SCHEMBL502785

COC(=O)Cc1ccc(Br)cc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP4F2 P78329 1/20 0.63
CYP4A11 Q02928 1/20 0.63
L3MBTL1 Q9Y468 2/20 0.57
KDM4E B2RXH2 2/20 0.57
GLA P06280 1/20 0.57
SMN1; SMN2 Q16637 3/20 0.55
NPC1 O15118 1/20 0.55
TP53 P04637 1/20 0.55
RAB9A P51151 1/20 0.55
KMT2A Q03164 4/20 0.54
HSP90AB1 P08238 1/20 0.52
ALDH1A1 P00352 5/20 0.51
GAA P10253 1/20 0.51
GFER P55789 1/20 0.51
HPGD P15428 1/20 0.51
MEN1 O00255 3/20 0.50
LMNA P02545 1/20 0.49
MAPK1 P28482 1/20 0.49
HTT P42858 1/20 0.49
EGFR P00533 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5536942 0.94 CYP4F2 (0.58) CYP4F2CYP4A11L3MBTL1KDM4EGLA
SCHEMBL31324172 0.91 SMN1; SMN2 (0.56) CYP4F2CYP4A11L3MBTL1KDM4EGLA
SCHEMBL7433303 0.89 CYP4F2 (0.53) CYP4F2CYP4A11L3MBTL1KDM4EGLA
SCHEMBL4113212 0.89 CYP4F2 (0.76) CYP4F2CYP4A11L3MBTL1KDM4ESMN1; SMN2
SCHEMBL20547390 0.88 CYP4F2 (0.51) CYP4F2CYP4A11L3MBTL1KDM4EGLA
SCHEMBL7960432 0.86 L3MBTL1 (0.53) CYP4F2CYP4A11L3MBTL1KDM4EGLA
SCHEMBL31324169 0.84 SMN1; SMN2 (0.50) CYP4F2CYP4A11L3MBTL1KDM4EGLA
SCHEMBL334884 0.83 CYP4F2 (0.63) CYP4F2CYP4A11L3MBTL1KDM4ESMN1; SMN2
SCHEMBL10046806 0.82 ALDH1A1 (0.51) CYP4F2CYP4A11L3MBTL1KDM4ESMN1; SMN2
SCHEMBL5546570 0.81 CYP4F2 (0.66) CYP4F2CYP4A11L3MBTL1KDM4ESMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 955 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119822949-A Method for synthesizing loxoprofen sodium by using resin catalyst 烟台舜康生物科技有限公司 2025-04-15 CN claimed
CN-113980117-B Fenpyroximate antigen and preparation method and application thereof 西南大学 2024-07-12 CN claimed
CN-117986178-A Preparation method of Fu Kasai di-substituted impurity 江苏嘉逸医药有限公司 2024-05-07 CN claimed
CN-117820460-A Methoxypiperidine ethyl antigen and preparation method and application thereof 西南大学 2024-04-05 CN claimed
CN-116693440-A Method for removing palladium catalyst in Irelance intermediate VI synthesis process 江苏嘉逸医药有限公司 2023-09-05 CN claimed
CN-108997223-B Preparation method of 5- (4-bromophenyl) -4, 6-dichloropyrimidine 浙江先锋科技股份有限公司 2020-06-30 CN claimed
US-20200048206-A1 METHOD FOR PREPARING 5-(4-BROMOPHENYL)-4,6-DICHLOROPYRIMIDINE ZHEJIANG XIANFENG TECHNOLOGIES CO.,LTD (CN) 2020-02-13 US claimed
US-10556871-B1 Method for preparing 5-(4-bromophenyl)-4,6-dichloropyrimidine ZHEJIANG XIANFENG TECHNOLOGIES CO., LTD. (CN) 2020-02-11 US claimed
CN-108047072-A A kind of synthetic method of C14H10Cl2NNaO2 深圳华中科技大学研究院 2018-05-18 CN claimed
CN-107793323-A A kind of synthetic method of Diclofenac methyl esters 华中科技大学 2018-03-13 CN claimed
US-12637440-B2 Amide derivative useful as diacylglycerol acyltransferase 2 inhibitor, and use thereof LG CHEM, LTD. (KR) 2026-05-26 US disclosed
US-12630528-B2 Amino aryl derivative useful as diacylglycerol acyltransferase 2 inhibitor and use thereof LG CHEM, LTD. (KR) 2026-05-19 US disclosed
CN-119019333-B Indazole-pyrazole skeleton compound and application thereof 中国药科大学 2026-05-19 CN disclosed
US-20260130872-A1 Substituted Bicyclic Compounds, Compositions and Methods of Use DEEP APPLE THERAPEUTICS, INC. (US) 2026-05-14 US disclosed
US-20260115296-A1 COMPOUNDS AND METHODS FOR THE TARGETED DEGRADATION OF RAPIDLY ACCELERATED FIBROSARCOMA POLYPEPTIDES UNIV YALE (US) 2026-04-30 US disclosed
CN-87108095-A Benzofuran (or benzothiophene) derivatives and preparation method thereof 1988-06-15 CN disclosed
EP-0252670-A2 2-Substituted alkoxy-3-substituted-pyrazines TOYO JOZO KABUSHIKI KAISHA (JP) 1988-01-13 EP disclosed
EP-0020052-B1 NOVEL SUBSTITUTED NITRODIPHENYL ETHERS, HERBICIDAL COMPOSITIONS CONTAINING THEM, PROCESSES FOR THE PREPARATION THEREOF AND THE USE THEREOF FOR COMBATING WEEDS ROHM AND HAAS COMPANY (US) 1983-07-20 EP disclosed
EP-0066217-A1 Novel substituted nitrodiphenyl ethers, herbicidal compositions containing them, processes for the preparation thereof and the use thereof for combating weeds ROHM AND HAAS COMPANY (US) 1982-12-08 EP disclosed
EP-0020052-A1 Novel substituted nitrodiphenyl ethers, herbicidal compositions containing them, processes for the preparation thereof and the use thereof for combating weeds ROHM AND HAAS COMPANY (US) 1980-12-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260130872-A1 Substituted Bicyclic Compounds, Compositions and Methods of Use GIPR, GLP1R, SIGMAR1 CYP4F2 1235/4885CYP4A11 1286/4885L3MBTL1 2488/4885
US-10556871-B1 Method for preparing 5-(4-bromophenyl)-4,6-dichloropyrimidine ME1, DERA, ME2 CYP4F2 213/4885CYP4A11 550/4885L3MBTL1 2773/4885
US-20200048206-A1 METHOD FOR PREPARING 5-(4-BROMOPHENYL)-4,6-DICHLOROPYRIMIDINE ME1, DERA, ME2 CYP4F2 213/4885CYP4A11 550/4885L3MBTL1 2773/4885
US-12630528-B2 Amino aryl derivative useful as diacylglycerol acyltransferase 2 inhibitor and use thereof DGAT2, DGAT1, SOAT2 CYP4F2 566/4885CYP4A11 652/4885L3MBTL1 1846/4885
US-20260115296-A1 COMPOUNDS AND METHODS FOR THE TARGETED DEGRADATION OF RAPIDLY ACCELERATED FIBROSARCOMA POLYPEPTIDES CRBN, VHL, ADRM1 CYP4F2 3705/4885CYP4A11 4354/4885L3MBTL1 300/4885
US-12637440-B2 Amide derivative useful as diacylglycerol acyltransferase 2 inhibitor, and use thereof DGAT2, DGAT1, DLAT CYP4F2 1056/4885CYP4A11 1766/4885L3MBTL1 991/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.