Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 4/20 | 0.39 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7443775 | 0.89 | SMN1; SMN2 (0.51) | MAPTSMN1; SMN2PPARGPPARACTSK | |
| SCHEMBL7443714 | 0.81 | RAB9A (0.43) | RAB9AMAPTSMN1; SMN2THRBTP53 | |
| SCHEMBL2157110 | 0.77 | RAB9A (0.53) | RAB9ASMN1; SMN2THRBTP53CA12 | |
| SCHEMBL7443191 | 0.77 | CTSK (0.54) | SMN1; SMN2CTSKCACNA1BPOLBMEN1 | |
| SCHEMBL7433375 | 0.75 | RAB9A (0.40) | RAB9AMAPTSMN1; SMN2THRBTP53 | |
| SCHEMBL7440796 | 0.73 | CTSK (0.64) | CTSKCA1CA2 | |
| SCHEMBL7433111 | 0.73 | CTSK (0.49) | PPARGPPARACTSKCA1CA2 | |
| SCHEMBL7446907 | 0.73 | CTSK (0.56) | PPARGPPARACTSK | |
| SCHEMBL18173887 | 0.72 | PPARG (0.44) | RAB9AMAPTSMN1; SMN2PPARGPPARA | |
| SCHEMBL18173886 | 0.72 | PPARG (0.44) | RAB9AMAPTSMN1; SMN2PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6187905-B1 | PEPTIDE COMPOUND WHICH INHIBITS VIRAL PROTEINASES; VIRICIDES FOR HEPATITIS C, HEPATITIS G, AND HUMAN GB VIRUSES | HOFFMANN-LA ROCHE INC. | 2001-02-13 | — | — | US | disclosed |