Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 13/20 | 0.56 |
| ▸ | CTSS | P25774 | 5/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | CTSB | P07858 | 1/20 | 0.44 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 4/20 | 0.43 |
| ▸ | PPARG | P37231 | 3/20 | 0.43 |
| ▸ | ACE | P12821 | 1/20 | 0.42 |
| ▸ | PPARD | Q03181 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7437012 | 0.89 | CTSK (0.71) | CTSKCTSSCTSLCTSB | |
| SCHEMBL7439368 | 0.87 | CTSK (0.56) | CTSKCTSSCTSLCTSBGABRB1 | |
| SCHEMBL7430637 | 0.87 | CTSK (0.56) | CTSKCTSSCTSLCTSBGABRB1 | |
| SCHEMBL7447101 | 0.87 | CTSK (0.56) | CTSKCTSSCTSLCTSBGABRB1 | |
| SCHEMBL7444346 | 0.85 | CTSK (0.60) | CTSKCTSSCTSLCTSB | |
| SCHEMBL7435889 | 0.85 | CTSK (0.60) | CTSKCTSSCTSLCTSB | |
| SCHEMBL7442355 | 0.82 | CTSK (0.71) | CTSKCTSSCTSLCTSBPPARA | |
| SCHEMBL7440796 | 0.79 | CTSK (0.64) | CTSKCTSSCTSLCTSB | |
| SCHEMBL7443203 | 0.79 | CTSK (0.55) | CTSKCTSSCTSLCTSBGABRB1 | |
| SCHEMBL7433111 | 0.79 | CTSK (0.49) | CTSKCTSSCTSLCTSBPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6187905-B1 | PEPTIDE COMPOUND WHICH INHIBITS VIRAL PROTEINASES; VIRICIDES FOR HEPATITIS C, HEPATITIS G, AND HUMAN GB VIRUSES | HOFFMANN-LA ROCHE INC. | 2001-02-13 | — | — | US | disclosed |