Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM6B | O15054 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 9/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 8/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 8/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 5/20 | 0.55 |
| ▸ | RECQL | P46063 | 4/20 | 0.55 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.55 |
| ▸ | USP2 | O75604 | 2/20 | 0.55 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.55 |
| ▸ | HTR2A | P28223 | 2/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.55 |
| ▸ | LCK | P06239 | 2/20 | 0.55 |
| ▸ | EGFR | P00533 | 1/20 | 0.55 |
| ▸ | FYN | P06241 | 1/20 | 0.55 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.55 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.47 |
| ▸ | MME | P08473 | 1/20 | 0.47 |
| ▸ | ACE | P12821 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 8/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7436643 | 0.84 | SLC7A5 (0.51) | KDM4ESLC7A5MMEACEESR1 | |
| SCHEMBL7436072 | 0.82 | GRIA2 (0.48) | KDM4EHIF1ASLC7A5LMNA | |
| SCHEMBL328475 | 0.81 | MME (0.60) | KDM6BKDM4EHSD17B10HIF1ATDP1 | |
| SCHEMBL9787629 | 0.81 | MME (0.60) | KDM6BKDM4EHSD17B10HIF1ATDP1 | |
| SCHEMBL7441034 | 0.81 | ACACB (0.51) | LMNAALDH1A1MEN1KMT2APPARG | |
| SCHEMBL468823 | 0.81 | MME (0.60) | KDM6BKDM4EHSD17B10HIF1ATDP1 | |
| SCHEMBL29367167 | 0.81 | MME (0.60) | KDM6BKDM4EHSD17B10HIF1ATDP1 | |
| SCHEMBL7436981 | 0.81 | TACR1 (0.51) | MMEACECA2 | |
| SCHEMBL7434134 | 0.80 | CTRB1 (0.55) | PTGS1SLC7A5LMNACYP1A2RAB9A | |
| SCHEMBL7442013 | 0.80 | CTRB1 (0.55) | PTGS1SLC7A5LMNACYP1A2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4453003-A | ENZYME INHIBITORS, ANTIINFLAMMATORY AGENTS | UMEZAWA HAMAO (JP) | 1984-06-05 | — | — | US | disclosed |
| US-4391986-A | Process for producing threo-3-amino-2-hydroxybutanoyl-aminoacetic acids, as well as novel intermediates therefor and process for producing them | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1983-07-05 | — | — | US | disclosed |
| US-4281180-A | Process for producing threo-3-amino-2-hydroxybutanoyl-aminoacetic acids, as well as novel intermediated therefor and process for producing them | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1981-07-28 | — | — | US | disclosed |