SCHEMBL7442013

SCHEMBL7442013

CC(=O)N[C@H](Cc1ccccc1)[C@H](O)C(=O)O

nearest known ligand 0.60

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CTRB1 P17538 5/20 0.55
LMNA P02545 1/20 0.50
PYGL P06737 1/20 0.50
CTSS P25774 1/20 0.49
CTSK P43235 1/20 0.49
PAM P19021 1/20 0.49
NPC1 O15118 1/20 0.49
RAB9A P51151 1/20 0.49
ALPI P09923 1/20 0.49
PKM P14618 1/20 0.49
PTGS1 P23219 1/20 0.49
XIAP P98170 1/20 0.49
SLC7A5 Q01650 1/20 0.49
CYP1A2 P05177 1/20 0.47
MTNR1A P48039 1/20 0.46
MTNR1B P49286 1/20 0.46
GNPAT O15228 1/20 0.46
TACR1 P25103 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7434134 1.00 CTRB1 (0.55) CTRB1LMNAPYGLCTSSCTSK
SCHEMBL7438864 0.91 ACACB (0.56) CTRB1
SCHEMBL14570232 0.90 CTRB1 (0.55) CTRB1LMNAPYGLCTSSCTSK
SCHEMBL7436643 0.87 SLC7A5 (0.51) CTRB1SLC7A5
SCHEMBL7441034 0.87 ACACB (0.51) CTRB1LMNAPYGL
SCHEMBL10693913 0.86 CTRB1 (0.49) CTRB1LMNAPYGLCTSSCTSK
SCHEMBL7270681 0.86 CTRB1 (0.58) CTRB1LMNACTSSCTSKPAM
SCHEMBL7444226 0.86 ALDH1A1 (0.44) CTRB1CTSSCTSK
SCHEMBL7434156 0.86 ACACB (0.52) CTRB1CTSSCTSKNPC1RAB9A
SCHEMBL11028602 0.85 MTNR1A (0.47) CTRB1LMNAPYGLCTSSCTSK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115784918-B Preparation method of high-purity ubenimex intermediate 四川青木制药有限公司 2024-10-15 CN disclosed
CN-115784918-A Preparation method of high-purity ubenimex intermediate 四川青木制药有限公司 2023-03-14 CN disclosed
CN-101891647-B Preparation method for ubenimex APELOA KANGYU PHARMACEUTICAL CO LTD 2012-12-19 CN disclosed
CN-101891647-A Preparation method for ubenimex APELOA KANGYU PHARMACEUTICAL CO LTD 2010-11-24 CN disclosed
US-4983567-A Immunomodulators and methods of making same BIOMEASURE, INC. (US) 1991-01-08 US disclosed
US-4871870-A Immunomodulators and method of making same BIOMEASURE, INC. (US) 1989-10-03 US disclosed
EP-0283260-A1 Immunomodulators and method of making same BIOMEASURE, INC. (US) 1988-09-21 EP disclosed
US-4453003-A ENZYME INHIBITORS, ANTIINFLAMMATORY AGENTS UMEZAWA HAMAO (JP) 1984-06-05 US disclosed
US-4391986-A Process for producing threo-3-amino-2-hydroxybutanoyl-aminoacetic acids, as well as novel intermediates therefor and process for producing them NIPPON KAYAKU KABUSHIKI KAISHA (JP) 1983-07-05 US disclosed
US-4281180-A Process for producing threo-3-amino-2-hydroxybutanoyl-aminoacetic acids, as well as novel intermediated therefor and process for producing them NIPPON KAYAKU KABUSHIKI KAISHA (JP) 1981-07-28 US disclosed