Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 19/20 | 0.47 |
| ▸ | F2 | P00734 | 7/20 | 0.46 |
| ▸ | F7 | P08709 | 1/20 | 0.41 |
| ▸ | F3 | P13726 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7424650 | 0.81 | F2 (0.54) | F10F2 | |
| SCHEMBL7425222 | 0.81 | F10 (0.47) | F10F2 | |
| SCHEMBL7433462 | 0.78 | F10 (0.48) | F10F2 | |
| SCHEMBL7424795 | 0.77 | TDP2 (0.41) | — | |
| SCHEMBL7434152 | 0.68 | F2 (0.63) | F10F2 | |
| SCHEMBL7974185 | 0.68 | F2 (0.75) | F10F2 | |
| SCHEMBL7424278 | 0.68 | F2 (0.65) | F10F2 | |
| SCHEMBL7428572 | 0.67 | HDAC8 (0.38) | F10F2 | |
| SCHEMBL7420549 | 0.65 | F2 (0.60) | F10F2 | |
| SCHEMBL7427280 | 0.65 | F2 (0.55) | F10F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1107954-A1 | 2-OXO-$i(2H)-QUINOLINE DERIVATIVES | MERCK PATENT GmbH (DE) | 2001-06-20 | — | — | EP | disclosed |
| WO-2000012479-A1 | 2-OXO-2H-QUINOLINE DERIVATIVES | MERCK PATENT GMBH (DE) | 2000-03-09 | — | — | WO | disclosed |