Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.40 |
| ▸ | HTR3B | O95264 | 2/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.40 |
| ▸ | HTR3A | P46098 | 2/20 | 0.40 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.40 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.40 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.40 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7433662 | 1.00 | CYP2D6 (0.45) | CYP2D6MEN1KMT2AALDH1A1HTR3E | |
| SCHEMBL7397643 | 0.81 | ALDH1A1 (0.49) | CYP2D6MEN1KMT2AALDH1A1HTR3E | |
| SCHEMBL7397644 | 0.81 | ALDH1A1 (0.49) | CYP2D6MEN1KMT2AALDH1A1HTR3E | |
| Oxalic Acid SCHEMBL7395703 | 0.77 | ALDH1A1 (0.45) | CYP2D6MEN1KMT2AALDH1A1HTR3E | |
| SCHEMBL15632467 | 0.76 | ALDH1A1 (0.68) | CYP2D6MEN1KMT2AALDH1A1HTR3E | |
| SCHEMBL4756059 | 0.76 | ALDH1A1 (0.50) | CYP2D6MEN1KMT2AALDH1A1HTR3E | |
| SCHEMBL6794293 | 0.73 | MEN1 (0.51) | MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL9366512 | 0.73 | MEN1 (0.51) | MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL10165810 | 0.73 | LMNA (0.45) | MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL2257067 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0515537-A1 | SUBSTITUTED UREA COMPOUNDS AND THEIR PREPARATION AND USE. | NOVO NORDISK AS (DK) | 1992-12-02 | — | — | EP | disclosed |
| WO-1991012254-A1 | SUBSTITUTED UREA COMPOUNDS AND THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1991-08-22 | — | — | WO | disclosed |