Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.57 |
| ▸ | CASP3 | P42574 | 1/20 | 0.56 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 7/20 | 0.52 |
| ▸ | LMNA | P02545 | 5/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | SRC | P12931 | 1/20 | 0.46 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5486180 | 0.87 | CASP3 (0.58) | CYP3A4CASP3SENP6MAPTLMNA | |
| SCHEMBL15570068 | 0.86 | CYP3A4 (0.54) | CYP3A4CASP3SENP6MAPTLMNA | |
| SCHEMBL7436116 | 0.85 | CYP3A4 (0.60) | CYP3A4MAPTKDM4EKMT2APOLB | |
| SCHEMBL9362833 | 0.85 | CYP3A4 (0.50) | CYP3A4CASP3SENP6MAPTKDM4E | |
| SCHEMBL16361704 | 0.85 | CYP3A4 (0.50) | CYP3A4CASP3SENP6MAPTLMNA | |
| SCHEMBL28521117 | 0.82 | CASP3 (0.56) | CYP3A4CASP3SENP6MAPTLMNA | |
| SCHEMBL7438219 | 0.82 | MAPT (0.67) | CYP3A4CASP3SENP6MAPTLMNA | |
| SCHEMBL7495223 | 0.82 | LMNA (0.57) | CYP3A4MAPTLMNAHPGDRECQL | |
| SCHEMBL7408146 | 0.82 | GAA (0.53) | CYP3A4CASP3SENP6MAPTLMNA | |
| SCHEMBL4543074 | 0.79 | MAPT (0.63) | CYP3A4CASP3SENP6MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4322346-A | 5H-2,3-Benzodiazepine derivatives | KOROSI JENO | 1982-03-30 | — | — | US | disclosed |