Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | CES2 | O00748 | 1/20 | 0.49 |
| ▸ | CES1 | P23141 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.41 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.40 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7433697 | 0.82 | CYP3A4 (0.57) | LMNACYP3A4KMT2APOLBMAPT | |
| SCHEMBL9362833 | 0.79 | CYP3A4 (0.50) | CYP3A4KMT2APOLBMAPTMEN1 | |
| SCHEMBL3821131 | 0.79 | LMNA (0.64) | LMNAKMT2ACES2CES1MAPT | |
| SCHEMBL7436116 | 0.76 | CYP3A4 (0.60) | CYP3A4KMT2APOLBMAPTCYP1A2 | |
| SCHEMBL17770569 | 0.76 | LMNA (0.60) | LMNAKMT2APOLBCES2CES1 | |
| SCHEMBL16913355 | 0.75 | POLB (0.52) | CYP3A4KMT2APOLBMAPTHPGD | |
| SCHEMBL7437535 | 0.74 | LMNA (0.53) | LMNAKMT2ACES2CES1MAPT | |
| SCHEMBL3825882 | 0.74 | LMNA (0.59) | LMNAKMT2ACES2CES1MEN1 | |
| SCHEMBL15570068 | 0.74 | CYP3A4 (0.54) | LMNACYP3A4KMT2APOLBMAPT | |
| SCHEMBL16361704 | 0.74 | CYP3A4 (0.50) | LMNACYP3A4KMT2APOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4322346-A | 5H-2,3-Benzodiazepine derivatives | KOROSI JENO | 1982-03-30 | — | — | US | disclosed |