Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.58 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.58 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.58 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | CLEC4M | Q9H2X3 | 1/20 | 0.49 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.47 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2658810 | 0.87 | TP53 (0.50) | GABRA1GABRB2GABRB1GABRA3CLEC4M | |
| SCHEMBL1559220 | 0.87 | CLEC4M (0.49) | GABRA1GABRB2GABRB1GABRA3CLEC4M | |
| SCHEMBL7434700 | 0.86 | CLEC4M (0.54) | GABRA1GABRB2GABRB1GABRA3CLEC4M | |
| SCHEMBL2658889 | 0.86 | JAK2 (0.54) | GABRA1GABRB2GABRB1GABRA3HTT | |
| SCHEMBL2656845 | 0.84 | CLEC4M (0.46) | GABRA1GABRB2GABRB1GABRA3HTT | |
| SCHEMBL7439474 | 0.83 | AR (0.60) | GABRA1GABRB2HTTCLEC4MKMT2A | |
| SCHEMBL18832216 | 0.78 | GABRA1 (0.54) | GABRA1GABRB2GABRB1GABRA3HTT | |
| SCHEMBL2657032 | 0.78 | CLEC4M (0.51) | GABRA1GABRB2GABRB1GABRA3CLEC4M | |
| SCHEMBL2658905 | 0.77 | KDM4E (0.55) | GABRA1GABRB2GABRB1GABRA3CLEC4M | |
| SCHEMBL2659216 | 0.76 | TSHR (0.49) | GABRA1GABRB2GABRB1GABRA3HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6333336-B1 | GAMMA-AMINOBUTYRIC ACID RECEPTORS AS ANTICONVULSANTS FORMING THE COMPOUND BY AMIDATION | MERCK SHARP & DOHME LTD. (GB) | 2001-12-25 | — | — | US | disclosed |