Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLEC4M | Q9H2X3 | 1/20 | 0.54 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.52 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.52 |
| ▸ | MDM2 | Q00987 | 3/20 | 0.52 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.52 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.52 |
| ▸ | JAK2 | O60674 | 2/20 | 0.51 |
| ▸ | JAK3 | P52333 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7433705 | 0.86 | GABRA1 (0.58) | CLEC4MGABRA1GABRB2GABRB1GABRA3 | |
| SCHEMBL2658810 | 0.86 | TP53 (0.50) | CLEC4MGABRA1GABRB2MDM2GABRB1 | |
| SCHEMBL2658550 | 0.86 | CLEC4M (0.52) | CLEC4MGABRA1GABRB2MDM2GABRB1 | |
| SCHEMBL1559220 | 0.86 | CLEC4M (0.49) | CLEC4MGABRA1GABRB2GABRB1GABRA3 | |
| SCHEMBL2658889 | 0.85 | JAK2 (0.54) | CLEC4MGABRA1GABRB2GABRB1GABRA3 | |
| SCHEMBL2657032 | 0.85 | CLEC4M (0.51) | CLEC4MGABRA1GABRB2MDM2GABRB1 | |
| SCHEMBL2658905 | 0.84 | KDM4E (0.55) | CLEC4MGABRA1GABRB2GABRB1GABRA3 | |
| SCHEMBL2656845 | 0.83 | CLEC4M (0.46) | CLEC4MGABRA1GABRB2GABRB1GABRA3 | |
| SCHEMBL7439474 | 0.82 | AR (0.60) | CLEC4MGABRA1GABRB2MEN1KMT2A | |
| SCHEMBL10462527 | 0.82 | CSNK2A1 (0.47) | KDM4EMAPTALDH1A1LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6333336-B1 | GAMMA-AMINOBUTYRIC ACID RECEPTORS AS ANTICONVULSANTS FORMING THE COMPOUND BY AMIDATION | MERCK SHARP & DOHME LTD. (GB) | 2001-12-25 | — | — | US | disclosed |
| US-4964896-A | GAMETOCIDES | MONSANTO COMPANY (US) | 1990-10-23 | — | — | US | disclosed |
| US-4936904-A | Aryl-4-oxonicotinates useful for inducing male sterility in cereal grain plants | MONSANTO TECHNOLOGY LLC | 1990-06-26 | — | — | US | disclosed |
| US-4714492-A | HYBRIDIZATION AGENTS | ROHM AND HAAS COMPANY (US) | 1987-12-22 | — | — | US | disclosed |