Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 2/20 | 0.41 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | TDO2 | P48775 | 1/20 | 0.36 |
| ▸ | FASN | P49327 | 1/20 | 0.36 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7437714 | 0.89 | CYP1A2 (0.43) | POLBCYP2C9CYP1A2CYP2C19LTA4H | |
| SCHEMBL7431022 | 0.89 | CYP1A2 (0.47) | POLBCYP2C9CYP1A2CYP2C19LTA4H | |
| SCHEMBL7438701 | 0.89 | CYP1A2 (0.48) | POLBCYP2C9CYP1A2CYP2C19LTA4H | |
| SCHEMBL7440427 | 0.87 | SMN1; SMN2 (0.44) | CYP2C9CYP1A2CYP2C19LTA4HMAPT | |
| SCHEMBL7439108 | 0.86 | CYP1A2 (0.41) | POLBCYP2C9CYP1A2CYP2C19LTA4H | |
| SCHEMBL7442267 | 0.82 | SMN1; SMN2 (0.46) | POLBCYP2C9CYP1A2CYP2C19LTA4H | |
| SCHEMBL7432463 | 0.81 | HPGD (0.38) | CYP2C9CYP1A2CYP2C19LTA4HMAPT | |
| SCHEMBL7434576 | 0.81 | LNPEP (0.38) | POLBCYP2C9CYP1A2CYP2C19LTA4H | |
| SCHEMBL7438657 | 0.81 | L3MBTL1 (0.38) | CYP2C9CYP1A2CYP2C19LTA4HMAPT | |
| SCHEMBL7436532 | 0.80 | LNPEP (0.39) | POLBCYP2C9CYP1A2CYP2C19LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5710153-A | INTERLEUKIN CONVERTING ENZYME INHIBITORS | ONO PHRAMACEUTICAL CO., LTD. (JP) | 1998-01-20 | — | — | US | disclosed |
| EP-0761680-A2 | Tetrazole compounds having Interleukin-1beta converting enzyme inhibitory activity | ONO PHARMACEUTICAL CO., LTD. (JP) | 1997-03-12 | — | — | EP | disclosed |