Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 5/20 | 0.39 |
| ▸ | PSMB5 | P28074 | 3/20 | 0.39 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.39 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.39 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.39 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.39 |
| ▸ | PSMA1 | P25786 | 1/20 | 0.39 |
| ▸ | PSMA2 | P25787 | 1/20 | 0.39 |
| ▸ | PSMA3 | P25788 | 1/20 | 0.39 |
| ▸ | PSMA4 | P25789 | 1/20 | 0.39 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.39 |
| ▸ | PSMA5 | P28066 | 1/20 | 0.39 |
| ▸ | PSMB4 | P28070 | 1/20 | 0.39 |
| ▸ | PSMB6 | P28072 | 1/20 | 0.39 |
| ▸ | LONP1 | P36776 | 1/20 | 0.39 |
| ▸ | PSMB10 | P40306 | 1/20 | 0.39 |
| ▸ | PSMB3 | P49720 | 1/20 | 0.39 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.39 |
| ▸ | PSMA6 | P60900 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7434149 | 1.00 | MMP8 (0.41) | MMP8F2PSMB5PSMB8PSMB11 | |
| SCHEMBL7442754 | 0.89 | F2 (0.42) | MMP8F2PSMB5PSMB8PSMB11 | |
| SCHEMBL7442760 | 0.89 | F2 (0.42) | MMP8F2PSMB5PSMB8PSMB11 | |
| SCHEMBL7438592 | 0.85 | F2 (0.40) | MMP8F2PSMB5F10 | |
| SCHEMBL7438599 | 0.85 | F2 (0.40) | MMP8F2PSMB5F10 | |
| SCHEMBL8091458 | 0.84 | F2 (0.50) | MMP8F2PSMB5F10 | |
| SCHEMBL8091462 | 0.84 | F2 (0.50) | MMP8F2PSMB5F10 | |
| SCHEMBL7440263 | 0.82 | F2 (0.43) | F2F10 | |
| SCHEMBL7440257 | 0.82 | F2 (0.43) | F2F10 | |
| SCHEMBL7432914 | 0.81 | F2 (0.42) | F2F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5814622-A | COMPOUND USEFUL AS TRYPSIN LIKE SERINE PROTEASE AS THROMBIN INHIBITORS | ADIR ET COMPAGNIE (FR) | 1998-09-29 | — | — | US | disclosed |