Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 17/20 | 0.50 |
| ▸ | F10 | P00742 | 5/20 | 0.45 |
| ▸ | PLG | P00747 | 6/20 | 0.44 |
| ▸ | PLAT | P00750 | 6/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 5/20 | 0.44 |
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8091458 | 1.00 | F2 (0.50) | F2F10PLGPLATPRSS1 | |
| SCHEMBL7443009 | 0.92 | F2 (0.44) | F2F10PLGPLATPRSS1 | |
| SCHEMBL7440257 | 0.88 | F2 (0.43) | F2F10PLGPLATPRSS1 | |
| SCHEMBL7448489 | 0.88 | F2 (0.43) | F2F10PLGPLATPRSS1 | |
| SCHEMBL7440263 | 0.88 | F2 (0.43) | F2F10PLGPLATPRSS1 | |
| SCHEMBL7432914 | 0.87 | F2 (0.42) | F2F10PLGPLATPRSS1 | |
| SCHEMBL26616877 | 0.84 | CTRB1 (0.55) | MMP8PSMB5 | |
| SCHEMBL26616870 | 0.84 | CTRB1 (0.55) | MMP8PSMB5 | |
| SCHEMBL7434149 | 0.84 | MMP8 (0.41) | F2F10MMP8PSMB5 | |
| SCHEMBL7434145 | 0.84 | MMP8 (0.41) | F2F10MMP8PSMB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0792883-B1 | Novel derivates of boronic acid, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2000-12-20 | — | — | EP | disclosed |
| EP-0792883-A1 | Novel derivates of boronic acid, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1997-09-03 | — | — | EP | disclosed |