Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | PSMB5 | P28074 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CTSL | P07711 | 2/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP7 | P09237 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP12 | P39900 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27693745 | 0.83 | MME (0.53) | MMEALDH1A1GAACTSLCTSB | |
| SCHEMBL9831516 | 0.82 | MME (0.50) | MMECTSLCTSBCTSSCTSK | |
| SCHEMBL6854264 | 0.82 | MME (0.54) | MMECTSLCTSBCTSSCTSK | |
| SCHEMBL27675065 | 0.79 | MME (0.47) | MMEALDH1A1CTSLCTSBCTSS | |
| SCHEMBL9829010 | 0.78 | CTSL (0.51) | MMECTSLCTSBCTSSCTSK | |
| SCHEMBL10443778 | 0.78 | MME (0.42) | MMEALDH1A1GAACTSK | |
| SCHEMBL10443960 | 0.78 | ALDH1A1 (0.42) | MMEALDH1A1GAACTSLCTSB | |
| SCHEMBL7275108 | 0.77 | MME (0.47) | MMEALDH1A1MAPK1 | |
| SCHEMBL21288033 | 0.77 | HTT (0.42) | ALDH1A1PSMB5SMN1; SMN2 | |
| SCHEMBL1524821 | 0.76 | CTSK (0.52) | MMECTSLCTSBCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0296581-A2 | Amino acid 1,2-diketo derivatives as renin inhibitors | E.R. SQUIBB & SONS, INC. (US) | 1988-12-28 | — | — | EP | disclosed |