Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD2 | O96028 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 4/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | CDC25B | P30305 | 1/20 | 0.35 |
| ▸ | APAF1 | O14727 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30612673 | 1.00 | NSD2 (0.42) | NSD2ALDH1A1ALOX15CYP3A4TP53 | |
| SCHEMBL151025 | 1.00 | NSD2 (0.42) | NSD2ALDH1A1ALOX15CYP3A4TP53 | |
| SCHEMBL11551865 | 0.86 | NSD2 (0.47) | NSD2ALDH1A1ALOX15CYP3A4TP53 | |
| SCHEMBL150487 | 0.84 | ADRA2A (0.37) | NSD2ALDH1A1ALOX15CYP3A4MAPK1 | |
| SCHEMBL128462 | 0.82 | NSD2 (0.36) | NSD2ALDH1A1ALOX15CYP3A4TP53 | |
| SCHEMBL150568 | 0.82 | S100B (0.51) | ALDH1A1CYP3A4MAPK1TDP1HDAC1 | |
| SCHEMBL5512906 | 0.80 | S100B (0.38) | ALDH1A1TDP1CDC25BHPGDMEN1 | |
| SCHEMBL2061685 | 0.79 | ALDH1A1 (0.51) | NSD2ALDH1A1ALOX15CYP3A4TP53 | |
| SCHEMBL2430788 | 0.79 | ALDH1A1 (0.39) | NSD2ALDH1A1ALOX15CYP3A4TP53 | |
| SCHEMBL152875 | 0.79 | S100B (0.31) | CDC25B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2430007-A1 | METHODS OF CHEMICAL SYNTHESIS OF DIAMINOPHENOTHIAZINIUM COMPOUNDS INVOLVING THE USE OF PERSULFATE OXIDANTS | Wista Laboratories Ltd. (SG) | 2012-03-21 | — | — | EP | disclosed |
| WO-2010130977-A1 | METHODS OF CHEMICAL SYNTHESIS OF DIAMINOPHENOTHIAZINIUM COMPOUNDS INVOLVING THE USE OF PERSULFATE OXIDANTS | WISTA LABORATORIES LTD. (SG) | 2010-11-18 | — | — | WO | disclosed |