Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO1 | P15559 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.37 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA6 | P23280 | 1/20 | 0.36 |
| ▸ | CA5A | P35218 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5146530 | 0.81 | TLR8 (0.43) | KDM4ECYP1A2SMN1; SMN2TP53MEN1 | |
| SCHEMBL65738 | 0.80 | TLR8 (0.45) | NPC1ALDH1A1GAA | |
| SCHEMBL2252068 | 0.75 | MAPK1 (0.43) | NQO1KDM4EAKR1C3AKR1C2CYP11B1 | |
| SCHEMBL8558909 | 0.75 | NQO1 (0.54) | NQO1KDM4EAKR1C3AKR1C2CA12 | |
| SCHEMBL16166839 | 0.72 | TSHR (0.42) | NQO1KDM4ETSHRSMN1; SMN2MEN1 | |
| SCHEMBL3825385 | 0.72 | NQO1 (0.68) | NQO1KDM4EAKR1C3AKR1C2CA12 | |
| SCHEMBL29629327 | 0.72 | NQO1 (0.68) | NQO1KDM4EAKR1C3AKR1C2CA12 | |
| SCHEMBL8143760 | 0.71 | MAPT (0.39) | CYP1A2MEN1NPC1KMT2AALDH1A1 | |
| SCHEMBL8135485 | 0.70 | SLC6A2 (0.39) | KDM4ESMN1; SMN2MEN1NPC1KMT2A | |
| SCHEMBL17912833 | 0.69 | NQO1 (0.46) | NQO1KDM4EAKR1C3AKR1C2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0283310-B1 | N-BENZHYDRYL-SUBSTITUTED HETEROCYCLIC DERIVATIVES, THEIR PREPARATION AND THEIR USE | Sankyo Company Limited (JP) | 1993-05-26 | — | — | EP | disclosed |
| US-5028610-A | Calcium Channel Blockers | SANKYO COMPANY LIMITED (JP) | 1991-07-02 | — | — | US | disclosed |
| EP-0283310-A1 | N-Benzhydryl-substituted heterocyclic derivatives, their preparation and their use | Sankyo Company Limited (JP) | 1988-09-21 | — | — | EP | disclosed |