SCHEMBL65738

SCHEMBL65738

CCOc1[c]c2ccccc2cc1OCC

nearest known ligand 0.45

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TLR8 Q9NR97 2/20 0.45
ALDH1A1 P00352 1/20 0.39
MAPK10 P53779 1/20 0.38
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38
ALOX5 P09917 1/20 0.35
POLB P06746 1/20 0.35
L3MBTL1 Q9Y468 4/20 0.35
MAPT P10636 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
GLA P06280 1/20 0.35
GAA P10253 1/20 0.35
ADORA3 P0DMS8 1/20 0.35
ADORA2A P29274 1/20 0.35
ADORA1 P30542 1/20 0.35
PDE10A Q9Y233 1/20 0.34
LMNA P02545 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5146530 0.87 TLR8 (0.43) TLR8ALDH1A1MAPK10NPC1RAB9A
SCHEMBL4306786 0.83 TLR8 (0.48) TLR8ALDH1A1NPC1RAB9APOLB
SCHEMBL2459817 0.83 TLR8 (0.35) TLR8ALDH1A1MAPK10NPC1RAB9A
SCHEMBL8143760 0.82 MAPT (0.39) TLR8ALDH1A1NPC1RAB9APOLB
SCHEMBL8135485 0.81 SLC6A2 (0.39) TLR8NPC1RAB9APOLBL3MBTL1
SCHEMBL1396333 0.81 TLR8 (0.50) TLR8L3MBTL1MAPTGAALMNA
SCHEMBL8136490 0.80 NUDT1 (0.36) TLR8ALDH1A1NPC1RAB9AL3MBTL1
SCHEMBL7434645 0.80 NQO1 (0.41) ALDH1A1NPC1GAA
SCHEMBL8139702 0.78 GRM5 (0.42) ALDH1A1LMNA
SCHEMBL2257890 0.78 ALDH1A1 (0.42) TLR8ALDH1A1MAPK10NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 812 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0924205-B1 Arylpiperazines having activity at the serotonin 1a receptor LILLY CO ELI (US) 2005-05-25 EP claimed
US-20240241442-A1 Positive Resist Material And Patterning Process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2024-07-18 US disclosed
US-12013639-B2 Positive resist material and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2024-06-18 US disclosed
US-20240192591-A1 RESIST COMPOSITION AND PATTERN FORMING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2024-06-13 US disclosed
US-12001138-B2 Composition for forming silicon-containing resist underlayer film and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2024-06-04 US disclosed
US-11994799-B2 Negative resist composition and pattern forming process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2024-05-28 US disclosed
US-20240168378-A1 Positive Resist Material And Patterning Process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2024-05-23 US disclosed
US-20240168382-A1 RESIST COMPOSITION AND PATTERN FORMING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2024-05-23 US disclosed
US-20240168379-A1 Positive Resist Material And Patterning Process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2024-05-23 US disclosed
US-20240160101-A1 RESIST COMPOSITION AND PATTERN FORMING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2024-05-16 US disclosed
EP-1096318-A1 Resist composition and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2001-05-02 EP disclosed
EP-1085377-A1 Resist compositions and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2001-03-21 EP disclosed
EP-1053985-A1 Resist compositions and patterning process Shin-Etsu Chemical Co., Ltd. (JP) 2000-11-22 EP disclosed
US-6147249-A ESTER COMPOUND CAPABLE OF FORMING ACID-DECOMPOSABLE POLYMER WHICH CAN BE BLENDED AS BASE RESIN TO FORMULATE RESIST COMPOSITION HAVING HIGHER SENSITIVITY, RESOLUTION AND ETCHING RESISTANCE THAN CONVENTIONAL RESIST COMPOSITIONS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2000-11-14 US disclosed
EP-1031879-A1 Novel ester compounds, polymers, resist compositions and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2000-08-30 EP disclosed
EP-1004568-A2 Novel ester compounds, polymers, resist compositions and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2000-05-31 EP disclosed
US-5972560-A A CROSSLINKED POLYSILOXANE PHOTOACID GENERATOR HAVING HIGH TRANSPARENCY, HIGH RESOLUTION, IMPROVED LATITUDE OF EXPOSURE, PROCESS ADAPTABILITY, AND FOR PRECISE MICRO-PROCESSING SHIN-ETSU CHEMICAL CO., LTD. (JP) 1999-10-26 US disclosed
EP-0283310-B1 N-BENZHYDRYL-SUBSTITUTED HETEROCYCLIC DERIVATIVES, THEIR PREPARATION AND THEIR USE Sankyo Company Limited (JP) 1993-05-26 EP disclosed
US-5028610-A Calcium Channel Blockers SANKYO COMPANY LIMITED (JP) 1991-07-02 US disclosed
EP-0283310-A1 N-Benzhydryl-substituted heterocyclic derivatives, their preparation and their use Sankyo Company Limited (JP) 1988-09-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240168378-A1 Positive Resist Material And Patterning Process HNRNPU, DSTN, NSUN2 TLR8 3542/4885ALDH1A1 3565/4885MAPK10 1211/4885
US-11994799-B2 Negative resist composition and pattern forming process GABRE, ZW10, VIM TLR8 4629/4885ALDH1A1 4756/4885MAPK10 1587/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.