Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AIMP2 | Q13155 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | PLAU | P00749 | 1/20 | 0.59 |
| ▸ | HPN | P05981 | 1/20 | 0.59 |
| ▸ | CA2 | P00918 | 6/20 | 0.57 |
| ▸ | CA1 | P00915 | 5/20 | 0.57 |
| ▸ | CA9 | Q16790 | 4/20 | 0.57 |
| ▸ | CA4 | P22748 | 1/20 | 0.57 |
| ▸ | MMP2 | P08253 | 4/20 | 0.56 |
| ▸ | MMP1 | P03956 | 3/20 | 0.56 |
| ▸ | MMP9 | P14780 | 3/20 | 0.56 |
| ▸ | MMP13 | P45452 | 3/20 | 0.56 |
| ▸ | MMP3 | P08254 | 2/20 | 0.56 |
| ▸ | MMP7 | P09237 | 2/20 | 0.56 |
| ▸ | CA7 | P43166 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7066619 | 0.88 | MMP9 (0.71) | AIMP2MEN1KMT2APLAUHPN | |
| SCHEMBL3969625 | 0.88 | MMP9 (0.71) | AIMP2MEN1KMT2APLAUHPN | |
| SCHEMBL11351046 | 0.88 | MMP9 (0.71) | AIMP2MEN1KMT2APLAUHPN | |
| SCHEMBL16388801 | 0.86 | CTSL (0.57) | MMP2MMP1MMP9MMP13MMP3 | |
| SCHEMBL27365155 | 0.86 | MMP2 (0.64) | AIMP2MEN1KMT2APLAUHPN | |
| SCHEMBL29827373 | 0.85 | KMT2A (0.58) | AIMP2MEN1KMT2APLAUHPN | |
| SCHEMBL19000609 | 0.84 | TDP1 (0.53) | AIMP2MEN1KMT2APLAUHPN | |
| SCHEMBL29999340 | 0.84 | AIMP2 (0.57) | AIMP2MEN1KMT2APLAUHPN | |
| SCHEMBL6194686 | 0.84 | AIMP2 (0.57) | AIMP2MEN1KMT2APLAUHPN | |
| SCHEMBL7264763 | 0.83 | AIMP2 (0.56) | AIMP2MEN1KMT2APLAUHPN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4826815-A | HYPOTENSIVE | ABBOTT LABORATORIES (US) | 1989-05-02 | — | — | US | disclosed |
| US-4645759-A | HYPOTENSIVE AGENTS | ABBOTT LABORATORIES (US) | 1987-02-24 | — | — | US | disclosed |
| EP-0172347-A2 | Renin inhibiting compounds | ABBOTT LABORATORIES (US) | 1986-02-26 | — | — | EP | disclosed |